目的 · 探讨二维超声联合四维彩色多普勒超声在子宫占位性病变诊断中的应用价值。方法 · 纳入 2015 年 3 月—2016 年 2 月 西南医科大学附属医院诊治的子宫占位性病变患者75 例，对患者进行二维和四维彩色多普勒超声检查，确定病变部位、病变数量、 病变性质以及恶性病变的临床分期，分析超声检查的准确率。结果 · 75 例子宫占位性病变中，子宫内膜癌 26 例，子宫肌瘤 21 例，子 宫息肉16 例，子宫腺肌病12 例；二维超声联合四维彩色多普勒超声对子宫占位性病变的诊断准确率为88.0%，明显高于二维超声 （64.0%），差异具有统计学意义（P<0.05）。对子宫内膜癌临床分期的诊断，二维超声联合四维彩色多普勒超声诊断准确率为 88.5%， 明显高于传统二维超声（61.5%），差异具有统计学意义（P<0.05）。 结论 · 相对二维超声检查，二维超声联合四维彩色多普勒超声能 够提高子宫占位性病变的诊断准确率，更准确地对子宫内膜癌进行术前临床分期，为治疗方案的制定提供依据。

 Objective · To evaluate the clinical value of two-dimensional ultrasound combined with four-dimensional color Doppler ultrasound in the diagnosis of uterine space-occupying lesion.  Methods · A total of 75 patients with uterine space-occupying lesion were enrolled in this study from March 2015 to February 2016 at Hospital of Southwest Medical University. Patients received both two-dimensional ultrasound and four-dimensional color Doppler ultrasound to determine the location, number and nature of the lesions, as well as the clinical staging of malignant lesions, then the diagnostic accuracy was evaluated.  Results · Among 75 patients, there were 26 cases with endometrial carcinoma, 21 cases with hysteromyoma, 16 cases with metropolypus, and 12 cases with uterine adenomyosis. The diagnostic accuracy of two-dimensional ultrasound combined with four-dimensional color Doppler ultrasound for the uterine space-occupying lesion was 88.0%, which was significantly higher than that of two-dimensional ultrasound (64.0%) (P<0.05). What's more, the diagnostic accuracy of two-dimensional ultrasound combined with four-dimensional color Doppler ultrasound for the clinical staging of endometrial carcinoma was 88.5%, which was significantly higher than that of two-dimensional ultrasound (61.5%) (P<0.05).  Conclusion · Two-dimensional ultrasound combined with four-dimensional color Doppler ultrasound is more effective to improve the diagnostic accuracy of uterine space occupying lesion and clinical staging of endometrial carcinoma in comparison with two-dimensional ultrasound, which will favor the clinical strategy for the treatment of uterine space-occupying lesion.