目的 · 探讨成人横纹肌肉瘤（RMS）的临床病理特点及预后。方法 · 回顾性分析 9 例 RMS 患者临床和病理资料，及免疫组 织化学检测结果。结果 · 该组患者平均年龄 (46.89±20.09) 岁，其中男性 6 例，女性 3 例。肿瘤分布范围广。组织学亚型包括胚胎性 RMS 6 例，腺泡状 RMS、多形性 RMS 和梭形细胞 RMS 各 1 例。免疫组织化学检测结果显示，横纹肌标记阳性例数分别为肌细胞生 成蛋白阳性 6 例、肌调节蛋白阳性 4 例、结蛋白阳性 8 例。7 例随访中无瘤生存仅 2 例，带瘤生存（均为术后出现复发或转移）2 例， 死于肿瘤 3 例。结论 · 该组成人 RMS 病例中以胚胎性 RMS 最常见，免疫组织化学检测有助于 RMS 的诊断。

 Objective · To investigate the clinicopathologic characteristics and prognosis of adult rhabdomyosarcoma (RMS).  Methods · The clinical and pathological data, immunohistochemical test results of 9 RMS were analyzed retrospectively.  Results · The information of 6 males and 3 females were collected in this research, whose average age was (46.89±20.09) years old. The tumors had a wide range distribution. The subtypes of histology included 6 cases of embryonal RMS, 1 case of alveolar RMS, 1 case of spindle cell RMS and 1 case of pleomorphic RMS. Immunohistochemically study showed that 6 cases were myogenin positive, 4 cases were MyoD1 positive and 8 cases were desmin positive. During the follow-up period of the 7 cases, only 2 patients survived free of tumors, 2 patients presented with tumor recurrence and metastasis after the operations, and 3 patients died of tumor.  Conclusion · In this study, embryonal RMS is the most common type, and immunohistochemistry test is helpful to diagnosis of RMS.