网络出版日期: 2021-05-27
基金资助
上海市申康医院发展中心临床技能与临床创新三年行动计划(16CR1007A);上海交通大学医学院附属第九人民医院临床研究助推计划(JYLJ001);上海交通大学医学院附属第九人民医院生物样本库专项基金(YBKA201902)
Image-fusion-based surgical navigation in sclerotherapy for low-flow vascular malformations in the risky regions of head and neck
Online published: 2021-05-27
Supported by
Three-Year Plan of Clinical Skills and Innovation Program of Shanghai Shenkang Hospital Development Center(16CR1007A);Clinical Research Program of Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine(JYLJ001);Special Fund for Biobank of Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine(YBKA201902)
目的·评估手术导航系统这一实时立体定向引导技术应用于头颈部危险区域低流量脉管畸形病灶硬化治疗的可行性和安全性。方法·回顾性纳入2017年5月—2019年9月在上海交通大学医学院附属第九人民医院整复外科接受了手术导航系统辅助硬化治疗的头颈部低流量脉管畸形患者。术前将患者计算机断层扫描图像和磁共振图像融合后,进行穿刺路径设计。术中利用导航系统,按预先设计的路径进行穿刺,通过数字减影血管造影验证穿刺结果。统计穿刺成功率和患者术后并发症情况。结果·共纳入10例头颈部低流量脉管畸形患者(6例眼眶内、4例咽部)30处病灶,治疗19次。初次治疗的平均年龄为20.9岁。穿刺成功率达到80.0%(24/30);除1次治疗后患者因硬化剂导致声门溃疡,继而引发肺炎外,未观察到其他并发症。结论·手术导航系统对头颈部危险区域低流量脉管畸形的硬化治疗是可行且安全的辅助技术。
顾豪 , 杨希 , 张紫旻 , 金云波 , 胡丽 , 陈辉 , 林晓曦 . 基于图像融合的手术导航系统在头颈部低流量脉管畸形硬化治疗中的应用[J]. 上海交通大学学报(医学版), 2021 , 41(5) : 695 -700 . DOI: 10.3969/j.issn.1674-8115.2021.05.023
·To evaluate the feasibility and safety of image-guided surgical navigation, a real-time stereotactic guidance technique, in sclerotherapy of low-flow vascular malformations in the risky regions of head and neck.
·The patients with low-flow vascular malformations in the heads or necks who underwent surgical navigation-assisted sclerotherapy in the Department of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine were retrospectively included. The preoperative CT images and magnetic resonance images were fused to design the puncture trajectory. During the operation, the navigation system was used to puncture according to the designed path, and the results were verified by digital subtraction angiography. The technical success rate of intralesional needle placement and postoperative complications were analyzed.
·A total of 19 procedures for 30 lesions performed on 10 patients with low-flow vascular malformations (6 cases with intraorbital lesions, and 4 cases with pharyngeal lesions) were included. The average age of initial procedure was 20.9 years. The technical success rate was 80.0% (24/30). No other complications were observed except a case of pneumonia caused by sclerosing agent-induced glottic ulcer after one procedure.
·Image-guided surgical navigation is a feasible and safe auxiliary technique for the lesions in the risky regions of head and neck.
1 | Mulliken JB, Glowacki J. Hemangiomas and vascular malformations in infants and children: a classification based on endothelial characteristics[J]. Plast Reconstr Surg, 1982, 69(3): 412-422. |
2 | Mulliken JB, Fishman SJ, Burrows PE. Vascular anomalies[J]. Curr Probl Surg, 2000, 37(8): 517-584. |
3 | 中华医学会整形外科分会血管瘤和脉管畸形学组. 血管瘤和脉管畸形的诊断及治疗指南(2019版)[J]. 组织工程与重建外科杂志, 2019, 15(5): 277-317. |
4 | Heit JJ, Do HM, Prestigiacomo CJ, et al. Guidelines and parameters: percutaneous sclerotherapy for the treatment of head and neck venous and lymphatic malformations[J]. J Neurointerv Surg, 2017, 9(6): 611-617. |
5 | Leonard S, Sinha A, Reiter A, et al. Evaluation and stability analysis of video-based navigation system for functional endoscopic sinus surgery on in vivo clinical data[J]. IEEE Trans Med Imaging, 2018, 37(10): 2185-2195. |
6 | Nesbit GM, Nesbit EG, Hamilton BE. Integrated cone-beam CT and fluoroscopic navigation in treatment of head and neck vascular malformations and tumors[J]. J Neurointerv Surg, 2011, 3(2): 186-190. |
7 | Partovi S, Lu ZA, Vidal L, et al. Real-time MRI-guided percutaneous sclerotherapy treatment of venous low-flow malformations in the head and neck[J]. Phlebology, 2018, 33(5): 344-352. |
8 | Unsgaard G, Ommedal S, Rygh OM, et al. Operation of arteriovenous malformations assisted by stereoscopic navigation-controlled display of preoperative magnetic resonance angiography and intraoperative ultrasound angiography[J]. Neurosurgery, 2005, 56(2): ons281-ons290. |
9 | Gonzalez LF, Albuquerque FC, Boom S, et al. Image-guided resection of embolized cerebral arteriovenous malformations based on catheter-based angiography[J]. Neurosurgery, 2010, 67(2): 471-475. |
10 | Raza SM, Papadimitriou K, Gandhi D, et al. Intra-arterial intraoperative computed tomography angiography guided navigation: a new technique for localization of vascular pathology[J]. Neurosurgery, 2012, 71(2 ): ons240-ons252. |
11 | Ernemann U, Westendorff C, Troitzsch D, et al. Navigation-assisted sclerotherapy of orbital venolymphatic malformation: a new guidance technique for percutaneous treatment of low-flow vascular malformations[J]. AJNR Am J Neuroradiol, 2004, 25(10): 1792-1795. |
12 | Mamlouk MD, Nicholson AD, Cooke DL, et al. Tips and tricks to optimize MRI protocols for cutaneous vascular anomalies[J]. Clin Imaging, 2017, 45: 71-80. |
13 | Compter I, Peerlings J, Eekers DB, et al. Technical feasibility of integrating 7 T anatomical MRI in image-guided radiotherapy of glioblastoma: a preparatory study[J]. MAGMA, 2016, 29(3): 591-603. |
14 | Chhabra A, Faridian-Aragh N, Chalian M, et al. High-resolution 3-T MR neurography of peroneal neuropathy[J]. Skeletal Radiol, 2012, 41(3): 257-271. |
15 | Hong GX, Yang ZY, Chu JP, et al. Three-dimensional MRI with contrast diagnosis of diseases involving peripheral oculomotor nerve[J]. Clin Imaging, 2012, 36(6): 674-679. |
16 | Algin O, Turkbey B. Evaluation of aqueductal stenosis by 3D sampling perfection with application-optimized contrasts using different flip angle evolutions sequence: preliminary results with 3T MR imaging[J]. AJNR Am J Neuroradiol, 2012, 33(4): 740-746. |
17 | Lu SS, Ge S, Su CQ, et al. MRI of plaque characteristics and relationship with downstream perfusion and cerebral infarction in patients with symptomatic middle cerebral artery stenosis[J]. J Magn Reson Imaging, 2018, 48(1): 66-73. |
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