网络出版日期: 2021-06-29
基金资助
国家自然科学基金(81671340);上海市卫生健康系统重要薄弱学科建设计划(2019ZB0201)
Influence of obsessive beliefs and impulsivity traits on symptom dimensions of obsessive-compulsive disorder patients
Online published: 2021-06-29
Supported by
National Natural Science Foundation of China(81671340);Shanghai Health System Important Weak Discipline Construction Plan(2019ZB0201)
目的·讨论不同强迫信念和冲动特质与强迫症不同症状亚型间的关系。方法·纳入未服用或停用2个月以上抗强迫药物的强迫症患者139例和健康对照110名,使用耶鲁布朗强迫量表(Yale-Brown Obsessive Compulsive Scale,Y-BOCS)、强迫信念问卷-44(Obsessive Beliefs Questionnaire-44,OBQ-44)、Barratt冲动性量表(Barratt Impulsiveness Scale,BIS-11)和强迫症状分类量表修订版(Obsessive Compulsive Inventory-Revised,OCI-R)分别评估其症状严重程度、强迫信念程度、冲动特质及症状维度。采用多元线性回归分析评估强迫症患者的强迫信念与冲动特质对强迫症症状维度的影响。结果·强迫症患者的各临床量表分数都显著高于健康对照组(均P<0.05)。强迫检查水平(或严重度)受责任感/威胁评估(responsibility/threat estimate,RT)信念和运动冲动(motor impulsiveness,MI)的共同影响(B=0.053,P=0. 000;B=-2.000,P=0.011);强迫排序水平受完美主义/确定感(perfectionism/certainty,PC)信念影响显著(B=0.049,P=0.001);强迫思维水平受RT信念的影响(B=0.082,P=0.000);混合型症状水平受RT信念和注意冲动(cognitive impulsiveness,CI)的共同影响(B=0.038,P=0.006;B=0.248,P=0.044)。结论·具有不同强迫信念和冲动特质的强迫症患者会呈现不同症状亚型。
李璞玉 , 程佳月 , 顾秋梦 , 阮瀚阳 , 王勇 , 刘强 , 吴艳茹 , 王振 . 强迫症患者的强迫信念和冲动特质对症状维度的影响[J]. 上海交通大学学报(医学版), 2021 , 41(6) : 756 -760 . DOI: 10.3969/j.issn.1674-8115.2021.06.008
·To test the effects of obsessive beliefs and impulsivity traits on different subtypes of obsessive-compulsive (OCD).
·A total of 139 non-medicated OCD patients and 110 matched healthy controls (HCs) were enrolled. The clinical symptoms were evaluated separately using Yale-Brown Obsessive Compulsive Scale (Y-BOCS), Obsessive Beliefs Questionnaire-44 (OBQ-44), Barratt Impulsiveness Scale (BIS-11), and Obsessive Compulsive Inventory-Revised (OCI-R). Multiple linear regression analysis was used to evaluate the influence of obsessive beliefs and impulsive traits on symptom dimensions of obsessive-compulsive disorder.
·The scores of all clinical scales of OCD patients were significantly higher than those of HCs (P<0.05). Obtained by multiple regression, the checking score was affected by responsibility/threat estimate (RT) and motor impulsiveness (MI) (B=0.053, P=0.00; B=-2.000, P=0.011); the ordering score was significantly affected by the perfectionism/certainty (PC) belief (B=0.049, P=0.001); the score of obsessing was affected by the belief in RT (B=0.082, P=0.000); the neutralizing score was affected by both RT belief and cognitive impulsiveness (CI) (B=0.038, P=0.006; B=0.248, P=0.044).
·OCD patients with different obsessive-compulsive beliefs and impulsivity traits will conduct different symptoms.
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