上海交通大学学报（医学版）

上海交通大学学报（医学版） >

2021 , Vol. 41 >Issue 7: 959 - 962

DOI: https://doi.org/10.3969/j.issn.1674-8115.2021.07.018

综述

水凝胶缓释系统在牙周组织再生中的应用

  • 夏侗樑 ,
  • 董家辰 ,
  • 束蓉
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  • 上海交通大学医学院附属第九人民医院·口腔医学院牙周病科，上海市口腔医学重点实验室，上海市口腔医学研究所，国家口腔疾病临床研究中心，上海 200011
夏侗樑（1991—），男，硕士生；电子信箱：410106512@qq.com。

网络出版日期: 2021-08-03

基金资助

国家自然科学基金(81570977);上海市自然科学基金(18ZR1422400);上海交通大学医学院附属第九人民医院“交叉”基金(JYJC201904)

收起

Application of hydrogel sustained-release system to periodontal tissue regeneration

  • Tung-liang HSIA ,
  • Jia-chen DONG ,
  • Rong SHU
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  • Department of Periodontology, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine; Shanghai Key Laboratory of Stomatology, Shanghai Research Institute of Stomatology; National Clinical Research Center for Oral Diseases, Shanghai 200011, China

Online published: 2021-08-03

Supported by

National Natural Science Foundation of China(81570977);Natural Science Foundation of Shanghai(18ZR1422400);Cross-disciplinary Research Fund of Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine(JYJC201904)

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摘要

水凝胶作为一种新兴的功能高分子材料，具有较大的开发潜力，在生物工程中有着广泛的应用。且因其有着良好的生物相容性，在医学领域也逐渐受到重视。有研究表明水凝胶缓释系统与生长因子结合后能够很好地促进人牙周膜成纤维细胞的增殖与黏附，并有效地促进其向成骨细胞及成牙骨质细胞分化。该文就水凝胶于牙周组织再生中的应用作一简要综述。

关键词： 水凝胶; 牙周组织再生; 组织工程; 支架材料

本文引用格式

夏侗樑 , 董家辰 , 束蓉 . 水凝胶缓释系统在牙周组织再生中的应用[J]. 上海交通大学学报（医学版）, 2021 , 41(7) : 959 -962 . DOI: 10.3969/j.issn.1674-8115.2021.07.018

Abstract

As an emerging functional polymer material, hydrogel has great potential for development, and is widely used in bioengineering. Because of its good biocompatibility, it has also gradually received attention in the medical field. Some studies have shown that hydrogel sustained-release system can promote the proliferation and adhesion of human periodontal ligament fibroblasts and effectively promote their differentiation into osteoblasts and cementoblasts. This paper briefly reviews the application of hydrogel to periodontal tissue regeneration.

Key words： hydrogel; regeneration of periodontal tissue; tissue engineering; scaffold material

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