网络出版日期: 2021-08-03
基金资助
上海市精神心理疾病临床医学研究中心(19MC1911100);上海市卫生和计划生育委员会项目(201740089)
Review of the factors influencing bone metabolism in schizophrenia
Online published: 2021-08-03
Supported by
Shanghai Clinical Research Center for Mental Health(19MC1911100);Project of Shanghai Municipal Commission of Health and Family Planning(201740089)
轩红艳 , 王丽华 , 李华芳 . 精神分裂症患者骨代谢影响因素的研究进展[J]. 上海交通大学学报（医学版）, 2021 , 41(7) : 972 -976 . DOI: 10.3969/j.issn.1674-8115.2021.07.021
The patients with schizophrenia experience a higher rate of low bone mineral density, osteoporosis and fractures than the general population, which affects not only their quality of life but also their long-term outcomes. Previous studies have shown that there are many factors affecting individual bone metabolism, including drugs, gender, age, hypogonadism, lifestyle, etc. Combined with clinical research, this article summarizes three aspects, i.e.,the disease itself, the use of antipsychotics and the unhealthy lifestyle. This review aims to discuss the influencing factors of bone metabolism in the patients with schizophrenia, and then expound briefly on the diagnosis and intervention measures of osteoporosis, which may provide a reference for clinical prevention and intervention of osteoporosis in the patients with schizophrenia.
Key words： schizophrenia; osteoporosis; bone metabolism; antipsychotics
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