目的 建立人类免疫缺陷病毒/艾滋病（HIV/AIDS）国家模型，探索基于案例的动态、计算机可视化的HIV/AIDS教育方法。方法 根据撒哈拉以南非洲国家的典型数据建立参考模型。根据T21国家模型的基本设计理念，采用系统动力学方法建立HIV/AIDS国家模型，并结合T21国家模型进行人口、社会、经济的系统分析。结果 HIV/AIDS国家模型清晰地模拟了艾滋病50年的传播趋势及其对国家人口、经济和社会的影响。结论 HIV/AIDS国家模型能够直观地反映艾滋病对人口、社会、经济发展的危害，有助于艾滋病健康教育的推进。

Objective To establish spread and trends of human immunodeficiency virus/acquired immune-deficiency syndrome (HIV/AIDS) national model as well as to explore computer-visualised case-based pattern of HIV/AIDS education by HIV/AIDS at national levels. Methods A typical data from sub-Saharan African countries were used to design the reference mode. HIV/AIDS model based on the design concept of T21 national model was established in analysing the population, economy and society. Results The national model established and analysed revealed the trend of HIV/AIDS propagation and its corresponding impact on the population, economy and society identified over fifty years. Conclusion The HIV/AIDS national model besides illustrating the spread, trend and hazard of HIV/AIDS on the general population, it is a useful tool for health promotion and education for the entire population.