综述

脂联素血管保护机制研究进展

展开
  • 上海交通大学 |医学院附属新华医院内分泌科, 上海 200092
张凌娟(1983—), 女, 博士生;电子信箱: zhang.lingjuan@yahoo.com.cn。

网络出版日期: 2010-09-27

Research progress of vascular protection mechanism of adiponectin

Expand
  • Department of Endocrinology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200092, China

Online published: 2010-09-27

摘要

脂联素是一种由脂肪细胞分泌的血浆蛋白,具有心血管保护作用。脂联素通过多种信号通路,发挥抗炎、抗氧化、抗动脉粥样硬化、改善微循环及双向调节血管新生的作用。文章就脂联素血管保护机制的研究进展作一综述。

本文引用格式

张凌娟 . 脂联素血管保护机制研究进展[J]. 上海交通大学学报(医学版), 2010 , 30(9) : 1164 . DOI: 10.3969/j.issn.1674-8115.2010.09.035

Abstract

Adiponectin is an abundant plasma protein secreted from adipocytes that elicits protective effects in the vasculature and myocardium. Adiponectin suppresses oxidative stress, inhibits inflammatory signaling cascades, ameliorates microvascular circulation and regulates angiogenesis via multiple signal pathways. The research progress of vascular protection mechanism of adiponectin is reviewed in this paper.

文章导航

/