网络出版日期: 2010-11-29
Research progress of relationship between clozapine and metabolic syndrome
Online published: 2010-11-29
陈剑华, 刘登堂, 李 岩, 等 . 氯氮平与代谢综合征的研究进展[J]. 上海交通大学学报(医学版), 2010 , 30(11) : 1424 . DOI: 10.3969/j.issn.1674-8115.2010.11.026
Metabolic syndrome, including diabetes, increased fasting plasma glucose, abdominal obesity, high cholesterol and high blood pressure, is a cluster of risk factors for cardiovascular diseases. Clozapine is one of the atypical antipsychotics which have negative effects on body weight, plasma lipid concentration and plasma glucose control, and may increase the risks of suffering from metabolic syndrome. The relationship between clozapine and metabolic syndrome is reviewed in this paper.
Key words: antipsychotics; schizophrenia; metabolic syndrome
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