基因多态性与胃癌化疗敏感性的研究进展
网络出版日期: 2011-02-01
基金资助
上海市卫生局基金(2008135)
Research progress of gene polymorphisms and chemosensitivity for gastric cancer
Online published: 2011-02-01
Supported by
Shanghai Municipal Health Bureau Foundation, 2008135
郑磊贞, 王志杰 . 基因多态性与胃癌化疗敏感性的研究进展[J]. 上海交通大学学报(医学版), 2011 , 31(1) : 89 . DOI: 10.3969/j.issn.1674-8115.2011.01.021
Chemotherapy plays an important role in the treatment of gastric cancer, with fluorouracil and platinum being the common drugs. However, patients respond differently to the same drugs, the mechanism of which may be important to be clarified to improve the efficacy of chemotherapy. This review systematically highlights the relationship between gene polymorphisms and chemosensitivity for gastric cancer according to the latest studies, which may provide evidences for the personalised treatment for gastric cancer.
Key words: gastric cancer; chemosensitivity; polymorphisms
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