目的 总结巨大肺动静脉瘘的介入治疗方法及效果。方法 回顾9例引入血管直径>5 mm的巨大肺动静脉瘘患者介入治疗过程。介入治疗前患者均接受右心导管检查和肺动脉造影术以了解瘘管的形态、大小和走行，确定拟栓塞的引入血管并准确测量血管直径。选用Amplatzer Plug或国产PDA封堵器进行封堵。结果9例患者共计引入血管11条，均封堵成功；共置入Amplatzer Plug 6枚，国产PDA封堵器 4枚。术后股动脉血氧饱和度显著升高至接近正常水平。结论 对于引入血管直径>5 mm的巨大肺动静脉瘘，Amplatzer Plug或国产PDA封堵器经导管封堵是一种有效且安全的介入治疗方法。

Objective To summarize the procedures and outcomes of interventional therapy for huge pulmonary arteriovenous fistula. Methods The treatment procedures of 9 patients with huge pulmonary arteriovenous fistula whose inlet blood vessels were larger than 5 mm in diameter were retrospectively analysed. The appearance, size and route of the fistula were learned by right heart catheterization and pulmonary arteriography before interventional therapy, the inlet vessels to be occluded were determined, and the diameters were accurately measured. The occlusion was performed with Amplatzer Plug or domestic PDA occluders. Results The number of inlet blood vessels was 11 in 9 patients, and all the occlusion was successfully performed. Six Amplatzer Plug and 4 domestic PDA occluders were placed. Femoral arterial oxygen saturation significantly increased to the normal level. Conclusion Transcatheter occlusion of huge pulmonary arteriovenous fistula with inlet blood vessel larger than 5 mm in diameter by Amplatzer Plug or domestic PDA occlude is an effective and safe interventional therapy.