胃癌相关血清标志物的临床意义及研究进展
网络出版日期: 2011-04-28
Clinical value and research advances of serum tumor markers in gastric cancer
Online published: 2011-04-28
葛沁怡, 胡梅洁 . 胃癌相关血清标志物的临床意义及研究进展[J]. 上海交通大学学报(医学版), 2011 , 31(4) : 505 . DOI: 10.3969/j.issn.1674-8115.2011.04.029
Gastric carcinogenesis is one of the most commonly occurring malignant neoplasms in China, and early diagnosis and treatment are crucial to improving the quality of life and reducing mortality rates for patients with gastric cancer. Serumbased detection methods allow for a standardized and non-invasive approach to monitoring progression of gastric cancer. We therefore summarize four serum-based biomarkers (E-cadherin, Runx3, hGC-1 and 3 subtypes of VEGF family) for gastric cancer, categorized into groups of genes and proteins, and evaluate their individual values in detecting gastric cancer, surveillance and evaluating prognosis of patients with gastric cancer.
Key words: gastric cancer; biomarker; serum; diagnosis; prognosis; DNA methylation
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