
饮茶与卵巢癌患病风险相关的Meta分析
网络出版日期: 2011-06-27
Meta-analysis of correlation between tea consumption and risk of ovarian cancer
Online published: 2011-06-27
目的 通过Meta分析研究饮茶与卵巢癌患病风险的相关性。方法 在Pubmed、EMbase、CBMdisc、CNKI、万方数据库检索相关文献,建立一定的筛选标准,在群体研究中探究卵巢癌发病风险与饮茶的关系。检索年限为1995—2010年,采用RevMan 5.1.0软件完成Meta分析。结果 共纳入国内外病例对照试验和队列试验9项研究,包括69 786例参与者,其中病例4 571例,对照65 215例。Meta分析显示:饮用茶可以显著地降低女性患卵巢癌的风险(RR=0.82,95%CI=0.70~0.96,P<0.001);其中绿茶降低患病风险的作用更为显著(RR=0.69,95%CI=0.54~0.90,P=0.006)。结论 饮用茶可以在一定程度上降低女性卵巢癌的患病风险,其中绿茶的抗癌效果更为显著。
吴诗瑜, 李妙竹, 刘 延, 等 . 饮茶与卵巢癌患病风险相关的Meta分析[J]. 上海交通大学学报(医学版), 2011 , 31(6) : 840 . DOI: 10.3969/j.issn.1674-8115.2011.06.036
Objective To explore the correlation between tea consumption and risk of ovarian cancer through Meta-analysis. Methods Relative studies published between 1995 and 2010 about tea consumption and risk of ovarian cancer were searched in Pubmed, EMbase, CBMdisc, CNKI and Wanfang Data. All reports were systemically reviewed, and Meta-analysis was performed by RevMan 5.1.0 software. Results A total of 9 domestic and overseas case-control studies and cohort studies were included, with 4 571 cases and 65 215 controls. Meta-analysis revealed that tea consumption significantly decreased the risk of ovarian cancer (RR, 0.82; 95%CI, 0.70-0.96; P<0.001), and the effect was more significant for green tea consumption (RR, 0.69; 95%CI, 0.54-0.90; P=0.006). Conclusion Tea consumption, especially green tea consumption, may reduce the risk of ovarian cancer.
Key words: ovarian cancer; tea; anti-cancer; Meta-analysis
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