结核分枝杆菌最低抑菌浓度测定方法及临界值设置研究进展
网络出版日期: 2012-06-01
基金资助
“十一五”国家科技重大专项(2009ZX10003-017和2009ZX10004-313)
Research progress of minimum inhibitory concentration detection technology and breakpoint setting for Mycobacterium tuberculosis
Online published: 2012-06-01
Supported by
National Major Science and Technology Project of China in the “Eleventh Five-year Plan”, 2009ZX10003-017, 2009ZX10004-313
张朝宝, 王洪海, 张舒林 . 结核分枝杆菌最低抑菌浓度测定方法及临界值设置研究进展[J]. 上海交通大学学报(医学版), 2012 , 32(5) : 661 . DOI: 10.3969/j.issn.1674-8115.2012.05.029
Tuberculosis is the most common cause of death due to a single infectious agent. The emergence of drug resistance and multidrug resistance is one of the important causes for the epidemics and widespreading of tuberculosis. It is of vital importance to develop the standard and effective detection approach of minimum inhibitory concentration (MIC) and to set up the effective breakpoints in the fields of individualized treatment, detection of drug resistance and drug screening for tuberculosis. The research progress of MIC detection technology and breakpoints setting for Mycobacterium tuberculosis are reviewed in this paper.
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