
子宫内膜容受性标志物的研究进展
网络出版日期: 2012-08-29
Research progress of endometrial receptivity markers
Online published: 2012-08-29
张平贵, 冯 云 . 子宫内膜容受性标志物的研究进展[J]. 上海交通大学学报(医学版), 2012 , 32(8) : 1014 . DOI: 10.3969/j.issn.1674-8115.2012.08.012
The low implantation rate is one of the major issues in the field of reproductive medicine, which has not been solved nowadays, and it also remains the major rate-limiting step in the development of human-assisted reproductive technology. Successful implantation requires a vital embryo and receptive endometrium. However, a large number of clinical trials have found that even if the embryo quality is good, the embryo implantation rate is continued low. The endometrium receptivity damage may be the main factor leading to low implantation rate. The better establishment of endometrial receptivity state may promote embryo-endometrial cross-talk, allowing the embryo implantation. The identification of endometrial receptivity markers is a prerequisite for improving endometrial receptivity. In recent years, the assessment of endometrial receptivity has become a research hotspot in reproductive medicine. The endometrial receptivity markers such as pinopodes, leukemia inhibitory factor (LIF) and homeobox A10 (HOXA10) gene are introduced in this paper.
/
| 〈 |
|
〉 |