重要自身免疫性疾病的发病机制及其免疫干预策略
网络出版日期: 2012-09-29
基金资助
国家自然科学基金海外及港澳学者合作研究基金(30728008);NIH/NIAID(AI 1R21AI079724-01);NIH/NIAID(U19 AI083022 Project 2 & Core B)
Autoimmune diseases: immuno-pathogenic dissection and strategy exploration for immune intervention
Online published: 2012-09-29
沈 浩 , 王 颖 , 王佳琦 , 等 . 重要自身免疫性疾病的发病机制及其免疫干预策略[J]. 上海交通大学学报(医学版), 2012 , 32(9) : 1128 . DOI: 10.3969/j.issn.1674-8115.2012.09.003
Autoimmune diseases arise from inappropriate immune responses against molecules and organs normally present in the body, resulting in tissue damage and functional defects. Supported by “211 Project”, the research groups from Shanghai Institute of Immunology and Shanghai Institute of Rheumatology have been working cooperatively to explore the immuno-regulation and immuno-pathogenesis of important autoimmune disorders including systemic lupus erythematosus (SLE), rheumatoid arthritis (RA) and psoriasis (PS), in which facilitate the diagnosis and intervention of the diseases. One of the research achievements, the pathogenesis of SLE and its novel therapeutic strategy, was awarded the second prize of 2009 National Science and Technology Progress Award.
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