非典型抗精神病药物对脂联素的影响
网络出版日期: 2013-03-07
基金资助
国家自然科学基金面上项目(81171271);上海市科委自然基金项目(11ZR1431300);国家临床重点专科-上海市精神卫生中心(卫生部医政司2011-873)
Impact of atypical antipsychotics on adiponectin
Online published: 2013-03-07
Supported by
National Natural Science Foundation of China, 81171271; Shanghai Science and Technology Committee Foundation, 11ZR1431300; National Key Clinical Disciplines at Shanghai Mental Health Center, Office of Medical Affairs, the Ministry of Health of China, 2011-873
杨 琳, 陈剑华, 徐一峰 . 非典型抗精神病药物对脂联素的影响[J]. 上海交通大学学报(医学版), 2013 , 33(2) : 231 . DOI: 10.3969/j.issn.1674-8115.2013.02.021
Metabolic syndrome (MS) may be caused by atypical antipsychotics (AAPs), and the possible mechanisms have not been fully revealed. Adipocytes regulate energy metabolism through release of adipocytokines. Studies have demonstrated that the impact of AAPs on adipokines is one of the potential mechanisms of drug-induced MS, and adiponectin is an important adipocytokine closely related to MS. The association between AAPs-induced MS and adiponectin is reviewed in this paper.
Key words: antipsychotics; metabolic syndrome; adipocytokines; adiponectin
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