目的 了解女性性工作者（FSWs）和男男性行为者（MSM）对通过网络获取获得性免疫缺陷综合征（艾滋病）相关知识的态度及影响因素。方法 对新疆、四川、广西、重庆四省区市FSWs和MSM进行抽样问卷调查，内容包括社会人口学特征、行为特征、获得及希望获得艾滋病相关知识的途径等。结果 网络是MSM的首选途径，超过总人数的80%；对FSWs，通过网络获得及希望获得艾滋病相关知识者分别占27.54%和31.66%。Logistic回归分析结果显示：民族、婚姻状况、年龄、文化程度、工作地点和每周性服务次数是FSWs通过网络获取艾滋病相关知识的影响因素；民族、年龄、文化程度、是否通过网络寻找性伴是MSM接受网络获得艾滋病知识的影响因素。结论 MSM对网络传播的可接受性强，经网络获得健康教育的效果较好。针对不同FSWs群体，应采取不同的干预方式以获得更好的健康教育效果。

Objective To investigate the attitudes and influencing factors of obtaining information about human immunodeficiency virus/acquired immune deficiency syndrome(HIV/AIDS) via internet among female sex workers(FSWs) and men who have sex with men (MSM). Methods FSWs and MSM selected from Xinjiang, Sichuan, Guangxi and Chongqing were surveyed with questionnaires, which included demographics, behavior characteristics, ways to obtain information about HIV/AIDS and the desirable ways to obtain it. Results Internet was the first choice for more than 80% of MSM to obtain information about HIV/AIDS. For FSWs, 27.54% obtained information about HIV/AIDS via internet, and 31.66% were willing to obtain information via internet. Logistic regression analysis revealed that ethnics, marital status, age, education background, workplace and frequency of sex service per week were influencing factors of acceptability to obtain information about HIV/AIDS via internet among FSWs, and ethnics, age, education background and seeking sex partner through internet were influencing factors of acceptability among MSM. Conclusion Obtaining information about HIV/AIDS via internet is acceptable for MSM, and it is feasible and useful to conduct health education via internet for MSM. While viable methods should be adopted to conduct health education for FSWs in order to achieve better effects.