目的 探讨家庭照护对慢性病患儿家庭功能的影响，为有针对性地进行家庭干预提供依据。方法 选择北京和上海7家医院的618名慢性病患儿家属为研究对象，采用家庭照护和Feetham家庭功能量表对其进行调查。采用单因素方差及相关性检验分析家庭照护和家庭功能的影响因素，从单因素分析结果中选择P<0.05的变量建立多元分层回归模型。结果 患儿认可、疾病负担、生活困难、家长关系、居住城市、母亲在职、病程＜1年和疾病种类（遗传性或泌尿系统疾病）是家庭功能的预测因素。结论 家庭照护是影响慢性病患儿家庭功能的重要因素，着重改善家庭照护过程中的关键环节，能直接影响家庭功能的发挥。

Objective To investigate the impact of family management on family functioning of families with chronically ill children, and provide evidence for tailored family intervention. Methods A total of 618 primary caregivers for chronically ill children from 7 hospitals in Beijing and Shanghai were selected, and were surveyed with family management measure and Feetham family functioning survey. The influencing factors of family management and family functioning were identified by univariate analysis and correlation analysis, and the variables with P<0.05 in previous analysis were selected to enter the multiple regression model. Results Child´s daily life, condition management effort, family life difficulty, parental mutuality, living in urban area, employed mother, duration of condition (<1 year) and diagnosis (renal disorder or genetic condition) were predictors of family functioning. Conclusion Family management is an important determinant of family functioning. Improving the key aspects of family management may directly affect family functioning.