影响奥氮平诱导的代谢紊乱动物模型可重复性的因素
网络出版日期: 2013-05-28
基金资助
上海市浦江人才计划(10PJ1408800);国家自然科学基金(81171266);上海市科技创新计划(11140900400);教育部第43批留学回国人员科研启动基金;上海市公共卫生优秀学科带头人培养计划(GWDTR201230);国家自然科学基金(81271481)
Influencing factors of reproducibility on establishment of Olanzapine-induced metabolic disorder animal model
Online published: 2013-05-28
Supported by
Shanghai Pujiang Talent Program, 10PJ1408800; National Natural Science Foundation, 81171266; Shanghai Science and Technology Innovation Program, 11140900400; Foundation of the Ministry of Education of China for Returned Talents from Overseas; Shanghai Public Health Excellent Discipline Leader Program, GWDTR201230; National Natural Science Foundation of China, 81271481
张成芳, Dake Qi, 崔东红 . 影响奥氮平诱导的代谢紊乱动物模型可重复性的因素[J]. 上海交通大学学报(医学版), 2013 , 33(5) : 690 . DOI: 10.3969/j.issn.1674-8115.2013.05.037
Olanzapine-induced metabolic disorders have been increasingly concerned. However, the mechanism is still unknown. The establishment of an appropriate animal model to explore the mechanism is a most important way, and the stability and reproducibility of an animal model are of vital importance. In this paper, the studies on establishment of Olanzapine-induced metabolic disorder animal models are reviewed, and the influencing factors of the reproducibility of animal models are discussed, hoping to provide reference for the related research.
Key words: Olanzapine; metabolic disorder; animal model; reproducibility
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