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Study on factors affecting the gastric emptying in patients with type 2 diabetes mellitus
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FENG Ri-lu1, JIN Yun-qiu1, XU Hua1, SONG Shao-li2, LIU Wei1, MA Jing1   

  1. 1.Department of Endocrinology, 2. Department of Nuclear Medicine,Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200127, China
  • Online:2017-05-28 Published:2017-05-31
  • Supported by:

    Natural Science Foundation of China, 81670728；Science and Technology Commission of Shanghai Municipality, 14441903502；Incubating Program for Clinical Research and Innovation of Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, PYZY16-020

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Abstract:

Objective · To investigate the possible factors affecting the gastric emptying rate in patients with type 2 diabetes mellitus. Methods · 94 type 2 diabetic patients treated at the Department of Endocrinology of Renji Hospital affiliated to Shanghai Jiao Tong University School of Medicine from September 2013 to March 2014 were enrolled. The half gastric emptying time (T1/2) and retention at 120 min (R120 min) were measured. Results · Female patients had longer T1/2 (P=0.000) and higher R120 min (P=0.000) than male patients. The differences in age, duration of diabetes, BMI, blood glucose level, chronic diabetic complications, and gastrointestinal symptoms between normal and delayed gastric emptying groups were not statistically significant. Acarbose had no effect on the gastric emptying rate in type 2 diabetic patients. Conclusion · The gastric emptying rate in type 2 diabetic patients is associated with the gender and has no significant correlation with blood glucose level, chronic diabetic complications, gastrointestinal symptoms, and acarbose.

Key words: gastric emptying rate, type 2 diabetes, gender, blood glucose, complication