›› 2017, Vol. 37 ›› Issue (11): 1542-.doi: 10.3969/j.issn.1674-8115.2017.11.016

Previous Articles     Next Articles

Clinical characteristics and prognostic factors of pelvic chondrosarcoma#br#

ZHAO Qi-wu, WANG Ji-zhuang, ZHANG Wei-bin, SHEN Yu-hui, WAN Rong   

  1. Department of Orthopaedic, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China
  • Online:2017-11-28 Published:2018-01-10
  • Supported by:
    Shanghai Municipal Education Commission—Gaofeng Clinical Medicine Grant Support, 20152204

Abstract: Objective · To summarize the clinical characteristics and prognostic factors of pelvic chondrosarcoma.  Methods · A total of 73 cases of chondrosarcoma  were collected, including 24 of pelvic. The clinical characteristics and prognostic factors of pelvic chondrosarcoma were analyzed by statistic methods.  Results · The ratio of men to women was 1.4:1,and the median age is 43.5 years old.  According to the classification of pelvic proposed by Enneking, there were 5 in region Ⅰ , 14 in region Ⅱ , and 5 in region Ⅲ . On histological review, 1 was grade 1, 15 were grade 2 ,and 8 were grade 3. The histologic types included 17 conventional, 3 dedifferentiated, 2 secondary, and 1 mesenchymal. The overall survival rates of pelvic chondrosarcoma were (82.2±8.1) %,(77.3±8.9) % and(52.4±12.1) % for 3, 5 and 10 years respectively. Local recurrence rate of pelvic chondrosarcoma (83.3%) was significantly higher than those of other sites (34.7%)(P=0.000), and the proportion of amputation was significantly higher than the other sites (50.0% vs 20.4%, P=0.000), but there was no significant difference in the overall survival between the two groups (P=0.216).  Conclusion · Pelvic chondrosarcoma have a higher local recurrence rate than the other sites and is tend to result in amputation. Early local recurrence after surgery indicates poor prognosis.

Key words: pelvic chondrosarcoma, prognostic factors, tumor recurrence

CLC Number: