Short- and long-term effects of frozen-thawed embryo transfer on offspring

doi:10.3969/j.issn.1674-8115.2021.05.016

Abstract

Abstract:

Frozen-thawed embryo transfer (FET) is one of the commonly used assisted reproductive technology. Because FET has the advantages of high cumulative pregnancy rate and low incidence of ovarian hyperstimulation syndrome, the number of offspring born through this technology is increasing year by year. Many studies have shown that the risks of preterm delivery, low birth weight and small for gestation age of FET offspring are lower than those of the offspring born in the fresh embryo transfer cycle. There is also evidence that the risks of macrosomia and large for gestational age of FET offspring are higher. At the same time, there are also reports on the long-term health status of FET offspring in childhood and adulthood. This paper reviews the short-term and long-term effects of FET on offspring and the causes.

Key words: assisted reproductive technology (ART), frozen-thawed embryo transfer (FET), offspring, short-term effect, long-term effect

CLC Number:

R711.6

Ning-xin QIN, Wen-long ZHAO, Zhi-yang ZHOU, Wei-hui SHI, Yan-ting WU, He-feng HUANG. Short- and long-term effects of frozen-thawed embryo transfer on offspring[J]. JOURNAL OF SHANGHAI JIAOTONG UNIVERSITY (MEDICAL SCIENCE), 2021, 41(5): 653-658.

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References 60

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