›› 2009, Vol. 29 ›› Issue (8): 990-.

• Review • Previous Articles     Next Articles

Research progress of spheroid colonies culture of liver cells

KUANG Jie, HAN Bao-san reviewer；PENG Cheng-hong, SHEN Bai-yong reviser   

  1. Department of Surgery, Center of Organ Transplantation, Shanghai Institute of Digestive Surgery, Ruijin Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200025, China
  • Online:2009-08-25 Published:2009-09-27
  • Supported by:

    National High Technology Research and Development Program of China, 863 program, 2007AA02Z487；National Natural Science Foundation of China, 30672043, 30772105；Shanghai Science and Technology Foundation, 07ZR14076

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Abstract:

Bioartificial liver plays an important role in the treatment of liver failure. Spheroid colonies culture is one of the main methods in culturing liver cells to maintain high density and biofunction for a long time. This paper reviews the influential factors and methods for spheroid colonies culture of liver cells.

Key words: bioartificial liver, hepatocyte, spheroid colony culture

CLC Number: