›› 2009, Vol. 29 ›› Issue (8): 994-.

• Review • Previous Articles     Next Articles

Research progress of relationship between mitochondrial DNA and bipolar disorder

ZHANG Chen reviewer;FANG Yi-ru reviser   

  1. Shanghai Mental Health Center, School of Medicine, Shanghai Jiaotong University, Shanghai 200030, |China
  • Online:2009-08-25 Published:2009-09-27
  • Supported by:

    National Key Science and Technology Project of “10th Five-Year Plan”, 2004BA720A21-02; National HighTech Research and Development Project, “863” Project, 2006AA02Z430; Shanghai Science and Technology Committee Foundation, 064119533

Abstract:

Mitochondria are essential elements that generate energy in cells. Mutations of human mitochondrial DNA may lead to aberrant oxidative phosphorylation and energy supplement in cells, indicating a possible relationship with bipolar disorder. The research progress on relationship between mitochondrial DNA and bipolar disorder is reviewed in this paper.

Key words: mitochondrial DNA, bipolar disorder, mutation

CLC Number: