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Characteristics and rare CT findings of hyaline vascular type Castleman's disease

ZHANG Jing1, LIN Xiao-zhu2, PAN Zi-lai1,2, CHEN Xiao-yan3, LI Wei-xia2, TANG Rong-biao2, CHEN Ke-min1,2, YAN Fu-hua2   

  1. 1.Department of Radiology, Ruijin Hospital North, Shanghai Jiao Tong University School of Medicine, Shanghai201800, China; 2.Department of Radiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai200025, China; 3.Department of Pathology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai200025, China
  • Online:2015-11-28 Published:2016-01-13

Abstract:

Objective  To explore and analyze the CT findings of hyaline vascular type Castleman’s disease and improve the accuracy of diagnosis. Methods  Data of 23 patients who were definitely diagnosed with hyaline vascular type Castleman’s disease by CT dual phase enhanced scan and pathological examination from July 2010 to May 2015 were retrospectively analyzed. Results  Among 23 cases of hyaline vascular type Castleman’s disease, focuses of 21 cases significantly and evenly enhanced, all located along main blood vessels, and were included in curving thick blood vessels. The focus of one case slightly and evenly enhanced, located nearby the ascending colon, and there were on main blood vessels nearby. Pelvic bones of one case showed osteogenetic and osteolytic destruction. Four cases had calcified focuses and the central area of one calcified focus was star shaped and edges of other three calcified focuses were linear, arc, and spotty, respectively. The focus of one case located in left neck and recurred in the same area one year after operation. Conclusion  Tumors of hyaline vascular type Castleman’s disease significantly enhance if they locate nearby main blood vessels and are included in curving thick blood vessels. Continuous, significant and even enhancement and calcification characteristics revealed by CT arteriovenous dual phase are important for diagnosis of hyaline vascular type Castleman's disease. Osteogenetic and osteolytic destruction and recurrence after operation are rare for limited hyaline vascular type Castleman's disease.

Key words: giant lymph node hyperplasia, hyaline vascular type, CT