JOURNAL OF SHANGHAI JIAOTONG UNIVERSITY (MEDICAL SCIENCE) ›› 2021, Vol. 41 ›› Issue (1): 95-98.doi: 10.3969/j.issn.1674-8115.2021.01.017

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Research status and prospect of transcranial focused ultrasound stimulation in treatment of psychiatric disorders

Zhao-lin ZHAI(), Deng-tang LIU()   

  1. Division of Psychotic Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai 200030, China
  • Online:2021-01-28 Published:2021-02-22
  • Contact: Deng-tang LIU;
  • Supported by:
    Funding Information] National Natural Science Foundation of China(81371479);Key Program of SMHC Clinical Research Center(CRC2017ZD03);Early Psychosis Program of Shanghai Mental Health Center(2013-YJTSZK-05)


As a non-invasive neuromodulation technique, transcranial focused ultrasound stimulation has the advantages of safety, high focused accuracy, deep penetration depth and easy compatibility with the synchronous recording of neuroimaging. Transcranial focused ultrasound stimulation has been used in the treatment of essential tremor, Parkinson's disease, brain tumors, etc. However, the progress in the area of psychiatry is still limited. The current research status of transcranial focused ultrasound stimulation in the treatment of psychiatric disorders is reviewed in this article, including the analysis of difficulties in its application and the prospect for the future direction.

Key words: transcranial focused ultrasound stimulation (tFUS), physiotherapy, neuromodulation, psychiatric disorders

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