JOURNAL OF SHANGHAI JIAOTONG UNIVERSITY (MEDICAL SCIENCE) ›› 2021, Vol. 41 ›› Issue (9): 1240-1245.doi: 10.3969/j.issn.1674-8115.2021.09.016

• Review • Previous Articles    

Research progress of imaging markers for identifying and predicting the progression of age-related macular degeneration

Yi-yang SHU(), Si-qi ZHANG, Hai-yun LIU()   

  1. Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine; National Clinical Research Center for Eye Diseases; Shanghai Key Laboratory of Ocular Fundus Diseases; Shanghai Engineering Center for Visual Science and Photomedicine; Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Diseases, Shanghai 200080, China
  • Received:2020-11-24 Online:2021-08-24 Published:2021-08-24
  • Contact: Hai-yun LIU E-mail:shuyiyang@sjtu.edu.cn;drliuhaiyun@126.com
  • Supported by:
    National Key R&D Program of China(2016YFC0904800);National Science and Technology Major Project of China(2017ZX09304010)

Abstract:

With the increase in the number of age-related macular degeneration (AMD) patients, imaging markers with indicative value have been screened and applied to the initial screening of AMD, disease warning, recurrence reminder and treatment guidance to contribute to the early diagnosis and accurate treatment for AMD patients. In clinical practice, colour fundus photography, optical coherence tomography (OCT), optical coherence tomography angiography (OCTA) and fundus angiography are mostly used for image recognition and analysis. This article reviews the imaging markers for identifying and predicting the progression of early-, middle- and late-stage AMD, as well as predicting the recurrence and prognosis of AMD, aiming to provide a theoretical basis and treatment guidance for clinical judgment.

Key words: age-related macular degeneration (AMD), imaging marker, optical coherence tomography (OCT), optical coherence tomography angiography (OCTA)

CLC Number: