Research progress of botulinum toxin A in treatment of neurogenic bladder

doi:10.3969/j.issn.1674-8115.2022.01.017

Abstract

Abstract:

In recent years, intradetrusor injection of botulinum toxin A (BTX-A) has achieved satisfactory therapeutic effects on the treatment of neurogenic bladder, improving the bladder function and reducing the lower urinary tract symptoms while improving patients' quality of life. In addition, this therapy has advantages including minimal invasiveness, mild side effects, and allowing repeated injections. At present, there is no international consensus on the injection plan for BTX-A. Therefore, based on the recent clinical research results, this paper reviews the mechanism of action, types, usage, therapeutic effects, influencing factors, as well as adverse reactions and contraindications of BTX-A, in an attempt to provide evidence for its clinical application.

Key words: botulinum toxin A, neurogenic bladder, neurogenic detrusor overactivity

CLC Number:

R694.5

Lin ZHANG, Zhong CHEN. Research progress of botulinum toxin A in treatment of neurogenic bladder[J]. JOURNAL OF SHANGHAI JIAOTONG UNIVERSITY (MEDICAL SCIENCE), 2022, 42(1): 113-118.

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References 38

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