Journal of Shanghai Jiao Tong University (Medical Science) ›› 2024, Vol. 44 ›› Issue (9): 1061-1068.doi: 10.3969/j.issn.1674-8115.2024.09.001

• Basic research •     Next Articles

Application of fluoroscopic stereophotogrammetric analysis in the detection of aseptic loosening of prostheses

YANG Han1(), LEI Hao2(), XU Bide1, WU Hao3, MA Xunjun4, HUANG Yanbo5, MAO Yuanqing6, ZHANG Jingwei6, WANG Jinwu6()   

  1. 1.Engineering Research Center of Digital Medicine and Clinical Translation, Ministry of Education of China, School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai 200030, China
    2.Shanghai Xuhui Excellent Medical and Industrial Intersection and Medical Artificial Intelligence Technology Innovation Center, Shanghai 200233, China
    3.School of Medicine, Shanghai University, Shanghai 200444, China
    4.School of Medical Information and Engineering, Xuzhou Medical University, Xuzhou 221004, China
    5.School of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai 200082, China
    6.Department of Orthopaedic Surgery, Shanghai Ninth People′s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200011, China
  • Received:2024-01-10 Accepted:2024-02-09 Online:2024-09-28 Published:2024-09-28
  • Contact: WANG Jinwu E-mail:yanghan0609@sjtu.edu.cn;haolei@emeai.org.cn;Jinwu_wang@163.com
  • Supported by:
    National Key R&D Program of China(2022YFF1202600);Science and Technology Innovation Action Plan of Shanghai Science and Technology Committee(22015820100);“Two-hundred Talents” Program of Shanghai Jiao Tong University School of Medicine(20152224);Translational Medicine Innovation Project of Shanghai Jiao Tong University School of Medicine(TM201613)

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Abstract:

Objective ·To verify the accuracy and clinical feasibility of fluoroscopic stereophotogrammetric analysis (FSA) technology based on two dimension (2D)-three dimension (3D) registration for early migration detection of aseptic loosening of joint prostheses. Methods ·2D-3D registration algorithms centering on the light source and projected object respectively in FSA technology were verified under various working conditions through image synthesis experiments, and the feasibility of clinical application was verified through real model experiments. The image synthesis experiment established a perspective projection environment with the same parameters as the real environment in a virtual environment, the 2D perspective images of the 3D model (bone or prosthesis) during the six degrees of freedom transformation were recorded, and the six degrees of freedom transformation of the 3D model was restored by using different 2D-3D registration algorithms. The error of each registration algorithm was calculated. For real model validation, the migration between bone and prosthesis after joint replacement surgery was simulated with a high precision bone prosthesis migration simulator. The 3D model of the bone or prosthesis was reconstructed by using computed tomograph (CT) images and optical scanning, and the 2D perspective images before and after prosthesis migration were captured by using a fluoroscopy device. The migration of the prosthesis was restored by using FSA technology based on 2D-3D registration, and the error of FSA technology was calculated. Results ·The accuracy of the 2D-3D registration algorithm centering on the light source was higher than that of the algorithm centering on the projected object under different working conditions. When the initial registration conditions were favorable, the algorithm centering on the light source reduced the rotation error compared to the algorithm centering on the projected object, with a statistical difference (P=0.021), and the displacement error decreases, with a significant statistical difference (P=0.000). Moreover, algorithms centering on the light sources required lower similarity and fewer registration times to meet clinical application requirements. Conclusion ·The accuracy of FSA technology based on 2D-3D registration in early migration detection of artificial joint prostheses meets clinical application requirements. This technology can warn of late aseptic loosening of prostheses by detecting early migration of prostheses after joint replacement surgery, and is expected to be applied to clinical practice through further research.

Key words: joint prosthesis, aseptic loosening, early migration detection, fluoroscopic analysis technology

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