Research progress of exosomes in stem cells

doi:10.3969/j.issn.1674-8115.2013.06.034

›› 2013, Vol. 33 ›› Issue (6): 868-.doi: 10.3969/j.issn.1674-8115.2013.06.034

• Review • Previous Articles Next Articles

Research progress of exosomes in stem cells

HU Guo-wen¹, WANG Yang², SHEN Xiao-li¹, DENG Zhi-feng^1,3

1.Department of Neurosurgery, the Second Affiliated Hospital of Nanchang University, Nanchang 330006, China, 2.Institute for Microsurgery of Extremities, the Sixth People's Hospital, Shanghai Jiaotong University, Shanghai 200233, China; 3.Department of Neurosurgery, the Sixth People's Hospital, Shanghai Jiaotong University, Shanghai 200233, China

Online:2013-06-28 Published:2013-06-28
Supported by:
National Natural Science Foundation of China，81170640，81272170

Abstract

Abstract:

Exosomes are small secreted vesicles, which play key roles in cell-to-cell communication. Exosomes can be released by different types of cells, and help to exchange membrane and transfer proteins, mRNA, microRNA and organelles between cells. Exosomes modulate normal physiological processes by transforming gene regulatory network or epigenetic reorganization. Recent studies have found that exosomes secreted by stem cells can transport mRNA, microRNA and proteins effectively, and play an important role in regulating tissue regeneration. The generation of exosomes and the research progress of exosomes in stem cells are reviewed in this paper.

Key words: exosome, stem cells, regenerative medicine

HU Guo-wen, WANG Yang, SHEN Xiao-li, et al. Research progress of exosomes in stem cells[J]. , 2013, 33(6): 868-.

[1]	Ting-wei LU, Jian-jun ZHANG, Wan-tao CHEN. Mechanisms related to regulation of natural killer cell activity by exosomes derived from malignant tumor cells [J]. JOURNAL OF SHANGHAI JIAOTONG UNIVERSITY (MEDICAL SCIENCE), 2021, 41(5): 659-664.
[2]	Run-ze YANG, Wen-ning XU, Huo-liang ZHENG, Sheng-dan JIANG. Effects of exosomes derived from human umbilical vein endothelial cells on apoptosis of pre-chondrogenic cells stimulated by inflammatory factors [J]. JOURNAL OF SHANGHAI JIAOTONG UNIVERSITY (MEDICAL SCIENCE), 2021, 41(2): 147-153.
[3]	Yan TONG, Jun-yan FANG, Hai DENG, A-hui SONG, Pu LI, Ying-li LIU. Different expression levels of exosomal miR-200a in peritoneal dialysis effluent from patients with different peritoneal transport characteristics and prediction of its biological function [J]. JOURNAL OF SHANGHAI JIAOTONG UNIVERSITY (MEDICAL SCIENCE), 2021, 41(1): 42-48.
[4]	ZHU Zheng-yang, WANG Cheng, JIANG Chen-yi, ZHAO Fu-jun. Aberrant RNA N6-methyladenosine modification causes tumorigenesis, progression and metastasis of malignant tumorsaffecting cancer stem cells [J]. , 2020, 40(3): 385-.
[5]	LIN Li, LI Hai-bo, XIA Fan, ZHOU Ji-xue, GUO Xiao-kui, ZHANG Shu-lin. Evaluation of exosome-derived miRNA-323a-3p human plasma as a potential biomarker for tuberculosis [J]. , 2020, 40(2): 171-.
[6]	LIANG Yu, JIANG Ming-jie, TIAN Ling. Advances in prostaglandin E2 reprogramming pancreatic cancer microenvironment [J]. , 2019, 39(8): 923-.
[7]	ZHU Chao-nan,CHEN Qin-wen,XIN Chen-ge,LI Hui. Inducible multiplexed CRISPR interference system in human embryonic stem cells [J]. , 2019, 39(5): 478-.
[8]	JIN Qiao-qiao, LIN Wen-zhen, YUAN Ke-yong, NIU Chen-guang, HUANG Zheng-wei. Extraction and identification of human stem cells the apical papilla derived-exosomes [J]. , 2019, 39(2): 126-.
[9]	HONG Ting, XUE Xiao-mei, HE Bin. Research progress of endogenous exosomes as nano drug delivery system for treatment of myocardial ischemia [J]. , 2018, 38(8): 984-.
[10]	CHEN Ming-jiao, FAN Xian-qun. Effect of hyaluronic acid-gelatin double-network hydrogel on osteogenic differentiation of rat bone marrow mesenchymal stem cells [J]. , 2018, 38(7): 722-.
[11]	QIU Xing-di, WU An-yue, LI Dong, HONG Zu-bei, GU li-ying, QIU Li-hua. Mechanism of TWEAK promoting macrophage-derived exosomal miR-7 to epithelial ovarian cancer cell through regulating Dicer [J]. , 2018, 38(7): 740-.
[12]	LIAO Wei-tang1, ZHANG Wen2. Research progress on role of exosomes in acute kidney injury [J]. , 2018, 38(7): 811-.
[13]	TIAN Ye, LIU Ao, DONG Rui, QI Xing, YI Jing, YANG Jie. Flow cytometry detection of cellular redox status with genetically encoded fluorescent probe [J]. , 2018, 38(1): 10-.
[14]	YAN Chun1, MA Yu-jie2, XIE Wei-yue1, YANG Qing-yuan3, SUN Feng-yong3, YANG Zhi2, XUE Song1, LIAN Feng1. Effect of gold nanoparticle on autophagy flux and exosome secretion of mesenchymal stem cells [J]. , 2018, 38(1): 42-.
[15]	YANG Qian, LIU Lan-xin, HUANG He-feng. Extraction and identification of exosomes in follicular fluid from patients with polycystic ovary syndrome and isolation and detection of miRNAs in exosomes#br# [J]. , 2017, 37(8): 1085-.

Research progress of exosomes in stem cells

PDF (PC)

Knowledge

Abstract

Cite this article

share this article

TrendMD

References

Related Articles 15

Recommended Articles

Metrics

Comments