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Research advances in Apolipoprotein A-Ⅰ and polycystic ovary syndrome

TONG La-juan, QIU Yan   

  1. Department of Assistant Reproductive Centre, the First Affiliated Hospital, Chongqing Medical University, Chongqing 400016, China
  • Online:2013-11-28 Published:2013-12-03


Apolipoprotein A-Ⅰ(ApoA-Ⅰ)is an important factor participating in the process of reverse cholesterol transport (RCT). In patients with polycystic ovary syndrome (PCOS), level of ApoA-Ⅰ was significantly low. The decreased expression of ApoA-Ⅰ could cause disorder of RCT, which may be connected with abnormal lipid metabolism and insulin resistance (IR) of PCOS patients.

Key words: apolipoprotein A-Ⅰ, polycystic ovary syndrome, reverse cholesterol transport, insulin resistance