• Original article (Clinical research) • Previous Articles     Next Articles

Clinical analysis of sequential therapy with partial splenic embolization in decreasing postoperative adverse reactions

SHI Min1, WANG Yu-gang1, WEI Jue1, WANG Ting1, MENG Wen-ying1, MA Jun2   

  1. Shanghai Tongren Hospital, Shanghai Jiao Tong University School of Medicine, 1.Department of Gastroenterology, 2.Department of Intensive Care Unit, Shanghai 200336, China
  • Online:2016-06-28 Published:2016-07-25
  • Supported by:

    Shanghai Municipal Health Bureau Key Disciplines Grant, ZK2015A24; Science Guide Foundation of the Science and Technology Commission of Shanghai Municipality, 14411973700; Shanghai Municipal Health Bureau, 20134100

Abstract:

Objective To explore the clinical value of sequential therapy with partial splenic embolization (PSE) in reducing postoperative adverse reactions. Methods Medical data of 98 patients with portal hypertension complicated with hypersplenism were retrospectively reviewed, which were divided into the sequential group (sequential PSE) and the control group (single PSE). The results of routine blood test, liver function, and incidence rate of post embolization syndrom,and postoperative complications were analyzed in patients of the two groups before and after the treatment. Results Compared with those before the treatment, white blood cells and platelets were significantly increased 2 weeks and 1 months after the treatment (P<0.01). Incidence rate of moderate and severe pain and high fever of the sequential group was obviously lower than that of the control group (P<0.01). The duration of moderate and severe pain and fever, and hospitalization day of the sequential group were relatively shorter (P<0.01). And the incidence of postoperative complications of the sequential group was obviously lower than that of the control group (P<0.01). Conclusion Sequential PSE can effectively improve the symptom of hypersplenism, and reduce the postoperative adverse reactions and complications of PSE.

Key words: hypersplenism, sequential therapy, embolization, therapy, complication