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Research progresses and applications of novel biomarkers in the diseases relevant to cardiac surgery

YUAN Zhi-ze, YE Xiao-feng, ZHAO Qiang   

  1. Department of Cardiac Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China
  • Online:2016-07-28 Published:2016-08-31


Cardiovascular diseases pose an increasingly serious threat to human health and surgical interventions are sometimes needed for some cardiovascular diseases, such as coronary atherosclerotic heart disease with severe triple vessel lesion. With the in-depth research on the pathogenesis, some biomarkers have been applied to screening, diagnosis, treatment, and prognosis evaluation of cardiovascular diseases. Early identification and intervention are crucial for decreasing cardiovascular events and improving prognosis. Cardiac surgery urgently needs novel biomarkers for providing early warnings for postoperative complications and prognosis. This paper reviews novel biomarkers relevant to the cardiac surgery that have been applied to the diagnosis of diseases or have the potential to be clinically applied in the future.

Key words: biomarker, early diagnosis, cardiac surgery