Abstract: Objective · To evaluate clinical indexes in predicting eosinophilic chronic rhinosinusitis (ECRS) in the one system. Methods · In this retrospective study, 89 chronic rhinosinusitis patients who underwent endoscopic sinus surgery in Renji Hospital, Shanghai Jiao Tong University School of Medicine were studied. Thirty-five patients were diagnosed as having ECRS, 54 having non-ECRS according to pathology. Peripheral blood eosinophil (EOS) absolute counts, peripheral blood EOS percentages (EOS%), E/M ratios (Lund-Mackay score ratio of ethmoid sinus to maxillary sinus) and Japanese Epidemiological Survey of Refractory Eosinophilic Chronic Rhinosinusitis (JESREC) scores were compared between the two groups. Receiver operating characteristic curves were constructed to assess the advantages and disadvantages of each predictive diagnostic index. Results · ① The peripheral blood EOS absolute and percentage, E/M ratio and JESREC score were higher in ECRS group than those in non-ECRS (P<0.01). ② AUC value of JESREC score was 0.893, peripheral blood EOS% was 0.877, peripheral blood EOS absolute was 0.870, and E/M ratio was 0.724. Conclusion · ① JESREC score, peripheral blood EOS absolute and percentage, and E/M ratio can be applied to predict ECRS. ② JESREC score, peripheral blood EOSabsoluteand peripheral blood EOS%show higherpredictingefficiency.

Key words: chronic rhinosinusitis, diagnose, eosinophil, JESREC score, E/M ratio