›› 2010, Vol. 30 ›› Issue (9): 1043-.doi: 10.3969/j.issn.1674-8115.2010.09.006

• Monographic report (Medical imaging and nuclear medicine) • Previous Articles     Next Articles

Clinical value of 18F-FDG PET/CT in detection of unexpected gastrointestinal lesions with high uptake

ZHANG Miao1, CHEN Gang1, WANG Chao1, HU Jia-jia1, ZHANG Min1, XU Hao-ping1, BAO Zhao-fang2, LI Biao1   

  1. 1.Department of Nuclear Medicine, 2.Exclusive Medical Care Centre, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China
  • Online:2010-09-25 Published:2010-09-27
  • Supported by:

    Shanghai Leading Academic Discipline Project, S30203

Abstract:

Objective To explore the clinical value of 18F-FDG PET/CT in detection of unexpected gastrointestinal lesions with high uptake. Methods The clinical data of 4 188 patients examined by 18F-FDG PET/CT were retrospectively analysed. Patients with unexpected gastrointestinal lesions with high uptake suspected of malignant tumors examined by 18F-FDG PET/CT, and without corresponding clinical symptoms and imaging abnormalities were selected. Forty-five out of 4 188 patients were enrolled, and the results of PET/CT examinations were compared with pathological findings. Results Unexpected gastrointestinal lesions with high uptake were detected in 45 out of 4 188 patients (1.1%). Among the 45 patients, 40 were confirmed by pathological examinations, and the other 5 were lost to follow up. Among the 40 patients, there were 23 cases (57.5%) of malignant lesions, 2 cases (5%) of benign lesions (precancerous lesions) and 15 cases (37.5%) of inflammatory lesions. SUVmax of gastrointestinal tumors group (9.8±4.5) was significantly higher than that of inflammatory lesions group (6.5±2.5)(P<0.05). Conclusion The possibility of unexpected gastrointestinal lesions with high uptake detected by 18F-FDG PET/CT to be malignant ones is higher, and attention should be paid to the early detection and timely treatment of gastrointestinal tumors without symptoms.

Key words: position emission tomography, gastrointestinal tract, oncology