Overweight and obesity are among the major public health concerns worldwide. Although conventional comprehensive interventions often enable short-term weight loss, weight regain remains prevalent. Cognitive behavioral therapy (CBT), a psychological intervention focused on modifying cognitions and behaviors, has been shown to help individuals with overweight or obesity achieve weight loss more effectively and healthily. It is regarded as one of the core evidence-based treatment modalities for weight management. From a neurobiological perspective, CBT enhances brain function, modulates the reward system, and alters neuroplasticity in individuals with excess weight, thereby significantly extending weight maintenance duration after intervention. Furthermore, CBT assists this population in identifying and modifying health-impairing thought patterns, fostering the adoption of healthy eating and physical activity habits, and effectively curbing weight regain. As CBT strategies are increasingly integrated into weight loss research, their application continues to evolve—shifting from traditional face-to-face sessions to digitally enabled interventions based on information and communication technologies. This transition not only improves intervention accessibility and engagement but also offers more personalized and convenient support for weight management. Future research should prioritize the local adaptation and technological innovation of CBT to enhance its scalability, positioning it as a vital tool in obesity prevention and control and thereby contributing substantially to improve public health outcomes.
为进一步提升CBT在超重和肥胖人群中的适用性，DALLE GRAVE等人［71］开发了一种新的疗法，即个性化肥胖认知行为干预（personalized cognitive behavioral therapy for obesity，CBT-OB）。区别于传统的CBT，CBT-OB首先基于受试者在干预初期的自我监测情况绘制专属的“认知图谱”。图谱囊括了受试者形成致胖生活方式的各类认知层面的影响因素，如问题性思维（我无法抵制甜食的诱惑）和前导刺激（我感到非常焦虑）等［72］。在随后的正式干预阶段，CBT-OB会针对图谱中表现出的主要认知问题，根据患者的个人需求提出特定的认知行为策略和方法。如此针对性的干预不仅可以让受试者的思维模式得到更加彻底且持久的改变，同时能够助力研究团队在干预后期准确找到促进受试者继续坚持的思维动机，并将这种思维模式主动应用到之后的减重过程中［73］。目前CBT-OB在研究环境和实际临床环境中都展现出良好的体重维持效果，能够保证受试者在6~12个月的干预期间没有体重反弹的趋势［74-75］。除了维持体重外，相比对照组，接受CBT-OB的受试者在长期的随访过程中都表现出明显的健康相关生活质量与身体成分模式的改善［76］。
尽管CBT-OB作为一种具有显著长期效果的体重管理方法已在实践中取得了巨大成功，但由于其干预持续时间较长（一般为1.5年），选择参与的受试者需要克服较大障碍，这也可能导致研究结果存在一定的志愿者偏倚［77］。为了解决这一问题，EGOSHI等人［78］对CBT-OB进行了改良，将这一新的基于CBT策略的干预命名为CBT-F（cognitive behavioral therapy for obesity modified as FIRE method）。CBT-F是一种结合了CBT-OB和药物疗法的独创治疗方法，它保留了CBT-OB中的重要干预模块即绘制“认知图谱”以及帮助受试者接纳行为上的改变，但也考虑到干预中药物的引入，增加了药物脱敏、克服药物不良反应和减少对药物的心理依赖等模块，整体干预周期仅需2个月。在超重和肥胖女性中，CBT-F组平均减重5.3 kg，对照组平均减重2.9 kg，差异具有统计学意义（P=0.003）［78］。可以看出，CBT-F持续时间短且药物治疗起效迅速，有望成为干预超重和肥胖人群有效且可持续的方法。
XU Wenyi was responsible for the conception, writing and revision of the paper, and ZHANG Zhiruo guided the writing and revision of the paper. Both authors have read the final version of paper and consented to submission.
利益冲突声明
所有作者声明不存在利益冲突。
COMPETING INTERESTS
Both authors declare no relevant conflict of interests.
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... 为进一步提升CBT在超重和肥胖人群中的适用性，DALLE GRAVE等人［71］开发了一种新的疗法，即个性化肥胖认知行为干预（personalized cognitive behavioral therapy for obesity，CBT-OB）.区别于传统的CBT，CBT-OB首先基于受试者在干预初期的自我监测情况绘制专属的“认知图谱”.图谱囊括了受试者形成致胖生活方式的各类认知层面的影响因素，如问题性思维（我无法抵制甜食的诱惑）和前导刺激（我感到非常焦虑）等［72］.在随后的正式干预阶段，CBT-OB会针对图谱中表现出的主要认知问题，根据患者的个人需求提出特定的认知行为策略和方法.如此针对性的干预不仅可以让受试者的思维模式得到更加彻底且持久的改变，同时能够助力研究团队在干预后期准确找到促进受试者继续坚持的思维动机，并将这种思维模式主动应用到之后的减重过程中［73］.目前CBT-OB在研究环境和实际临床环境中都展现出良好的体重维持效果，能够保证受试者在6~12个月的干预期间没有体重反弹的趋势［74-75］.除了维持体重外，相比对照组，接受CBT-OB的受试者在长期的随访过程中都表现出明显的健康相关生活质量与身体成分模式的改善［76］. ...
1
... 为进一步提升CBT在超重和肥胖人群中的适用性，DALLE GRAVE等人［71］开发了一种新的疗法，即个性化肥胖认知行为干预（personalized cognitive behavioral therapy for obesity，CBT-OB）.区别于传统的CBT，CBT-OB首先基于受试者在干预初期的自我监测情况绘制专属的“认知图谱”.图谱囊括了受试者形成致胖生活方式的各类认知层面的影响因素，如问题性思维（我无法抵制甜食的诱惑）和前导刺激（我感到非常焦虑）等［72］.在随后的正式干预阶段，CBT-OB会针对图谱中表现出的主要认知问题，根据患者的个人需求提出特定的认知行为策略和方法.如此针对性的干预不仅可以让受试者的思维模式得到更加彻底且持久的改变，同时能够助力研究团队在干预后期准确找到促进受试者继续坚持的思维动机，并将这种思维模式主动应用到之后的减重过程中［73］.目前CBT-OB在研究环境和实际临床环境中都展现出良好的体重维持效果，能够保证受试者在6~12个月的干预期间没有体重反弹的趋势［74-75］.除了维持体重外，相比对照组，接受CBT-OB的受试者在长期的随访过程中都表现出明显的健康相关生活质量与身体成分模式的改善［76］. ...
1
... 为进一步提升CBT在超重和肥胖人群中的适用性，DALLE GRAVE等人［71］开发了一种新的疗法，即个性化肥胖认知行为干预（personalized cognitive behavioral therapy for obesity，CBT-OB）.区别于传统的CBT，CBT-OB首先基于受试者在干预初期的自我监测情况绘制专属的“认知图谱”.图谱囊括了受试者形成致胖生活方式的各类认知层面的影响因素，如问题性思维（我无法抵制甜食的诱惑）和前导刺激（我感到非常焦虑）等［72］.在随后的正式干预阶段，CBT-OB会针对图谱中表现出的主要认知问题，根据患者的个人需求提出特定的认知行为策略和方法.如此针对性的干预不仅可以让受试者的思维模式得到更加彻底且持久的改变，同时能够助力研究团队在干预后期准确找到促进受试者继续坚持的思维动机，并将这种思维模式主动应用到之后的减重过程中［73］.目前CBT-OB在研究环境和实际临床环境中都展现出良好的体重维持效果，能够保证受试者在6~12个月的干预期间没有体重反弹的趋势［74-75］.除了维持体重外，相比对照组，接受CBT-OB的受试者在长期的随访过程中都表现出明显的健康相关生活质量与身体成分模式的改善［76］. ...
1
... 为进一步提升CBT在超重和肥胖人群中的适用性，DALLE GRAVE等人［71］开发了一种新的疗法，即个性化肥胖认知行为干预（personalized cognitive behavioral therapy for obesity，CBT-OB）.区别于传统的CBT，CBT-OB首先基于受试者在干预初期的自我监测情况绘制专属的“认知图谱”.图谱囊括了受试者形成致胖生活方式的各类认知层面的影响因素，如问题性思维（我无法抵制甜食的诱惑）和前导刺激（我感到非常焦虑）等［72］.在随后的正式干预阶段，CBT-OB会针对图谱中表现出的主要认知问题，根据患者的个人需求提出特定的认知行为策略和方法.如此针对性的干预不仅可以让受试者的思维模式得到更加彻底且持久的改变，同时能够助力研究团队在干预后期准确找到促进受试者继续坚持的思维动机，并将这种思维模式主动应用到之后的减重过程中［73］.目前CBT-OB在研究环境和实际临床环境中都展现出良好的体重维持效果，能够保证受试者在6~12个月的干预期间没有体重反弹的趋势［74-75］.除了维持体重外，相比对照组，接受CBT-OB的受试者在长期的随访过程中都表现出明显的健康相关生活质量与身体成分模式的改善［76］. ...
1
... 为进一步提升CBT在超重和肥胖人群中的适用性，DALLE GRAVE等人［71］开发了一种新的疗法，即个性化肥胖认知行为干预（personalized cognitive behavioral therapy for obesity，CBT-OB）.区别于传统的CBT，CBT-OB首先基于受试者在干预初期的自我监测情况绘制专属的“认知图谱”.图谱囊括了受试者形成致胖生活方式的各类认知层面的影响因素，如问题性思维（我无法抵制甜食的诱惑）和前导刺激（我感到非常焦虑）等［72］.在随后的正式干预阶段，CBT-OB会针对图谱中表现出的主要认知问题，根据患者的个人需求提出特定的认知行为策略和方法.如此针对性的干预不仅可以让受试者的思维模式得到更加彻底且持久的改变，同时能够助力研究团队在干预后期准确找到促进受试者继续坚持的思维动机，并将这种思维模式主动应用到之后的减重过程中［73］.目前CBT-OB在研究环境和实际临床环境中都展现出良好的体重维持效果，能够保证受试者在6~12个月的干预期间没有体重反弹的趋势［74-75］.除了维持体重外，相比对照组，接受CBT-OB的受试者在长期的随访过程中都表现出明显的健康相关生活质量与身体成分模式的改善［76］. ...
1
... 为进一步提升CBT在超重和肥胖人群中的适用性，DALLE GRAVE等人［71］开发了一种新的疗法，即个性化肥胖认知行为干预（personalized cognitive behavioral therapy for obesity，CBT-OB）.区别于传统的CBT，CBT-OB首先基于受试者在干预初期的自我监测情况绘制专属的“认知图谱”.图谱囊括了受试者形成致胖生活方式的各类认知层面的影响因素，如问题性思维（我无法抵制甜食的诱惑）和前导刺激（我感到非常焦虑）等［72］.在随后的正式干预阶段，CBT-OB会针对图谱中表现出的主要认知问题，根据患者的个人需求提出特定的认知行为策略和方法.如此针对性的干预不仅可以让受试者的思维模式得到更加彻底且持久的改变，同时能够助力研究团队在干预后期准确找到促进受试者继续坚持的思维动机，并将这种思维模式主动应用到之后的减重过程中［73］.目前CBT-OB在研究环境和实际临床环境中都展现出良好的体重维持效果，能够保证受试者在6~12个月的干预期间没有体重反弹的趋势［74-75］.除了维持体重外，相比对照组，接受CBT-OB的受试者在长期的随访过程中都表现出明显的健康相关生活质量与身体成分模式的改善［76］. ...
1
... 尽管CBT-OB作为一种具有显著长期效果的体重管理方法已在实践中取得了巨大成功，但由于其干预持续时间较长（一般为1.5年），选择参与的受试者需要克服较大障碍，这也可能导致研究结果存在一定的志愿者偏倚［77］.为了解决这一问题，EGOSHI等人［78］对CBT-OB进行了改良，将这一新的基于CBT策略的干预命名为CBT-F（cognitive behavioral therapy for obesity modified as FIRE method）.CBT-F是一种结合了CBT-OB和药物疗法的独创治疗方法，它保留了CBT-OB中的重要干预模块即绘制“认知图谱”以及帮助受试者接纳行为上的改变，但也考虑到干预中药物的引入，增加了药物脱敏、克服药物不良反应和减少对药物的心理依赖等模块，整体干预周期仅需2个月.在超重和肥胖女性中，CBT-F组平均减重5.3 kg，对照组平均减重2.9 kg，差异具有统计学意义（P=0.003）［78］.可以看出，CBT-F持续时间短且药物治疗起效迅速，有望成为干预超重和肥胖人群有效且可持续的方法. ...
2
... 尽管CBT-OB作为一种具有显著长期效果的体重管理方法已在实践中取得了巨大成功，但由于其干预持续时间较长（一般为1.5年），选择参与的受试者需要克服较大障碍，这也可能导致研究结果存在一定的志愿者偏倚［77］.为了解决这一问题，EGOSHI等人［78］对CBT-OB进行了改良，将这一新的基于CBT策略的干预命名为CBT-F（cognitive behavioral therapy for obesity modified as FIRE method）.CBT-F是一种结合了CBT-OB和药物疗法的独创治疗方法，它保留了CBT-OB中的重要干预模块即绘制“认知图谱”以及帮助受试者接纳行为上的改变，但也考虑到干预中药物的引入，增加了药物脱敏、克服药物不良反应和减少对药物的心理依赖等模块，整体干预周期仅需2个月.在超重和肥胖女性中，CBT-F组平均减重5.3 kg，对照组平均减重2.9 kg，差异具有统计学意义（P=0.003）［78］.可以看出，CBT-F持续时间短且药物治疗起效迅速，有望成为干预超重和肥胖人群有效且可持续的方法. ...
