上海交通大学学报（医学版）

上海交通大学学报（医学版）

• 病例报告 • 上一篇    

以甲状腺功能减退症合并全身性水肿、肺动脉高压为首发表现的POEMS综合征1例报道

成玮 1，蒋瑛 2，张维佳 3 ，李晓华 1，徐艳红 1，贝鹏剑 1   

  1. 1.上海中医药大学附属第七人民医院内分泌科，上海 200137；2.上海交通大学附属第一人民医院血液科，上海 200080；3.上海中医药大学附属岳阳医院内科，上海 200437
  • 出版日期:2017-01-28 发布日期:2017-01-19
  • 作者简介:成玮 (1978—)，女，副主任医师，硕士；电子信箱：zhou824@sina.com。

One case report of POEMS syndrome with hypothyroidism, systemic edema, and pulmonary hypertension as the initial manifestation

CHENG Wei1, JIANG Ying2, ZHANG Wei-jia3, LI Xiao-hua1, XU Yan-hong1, BEI Peng-jian1   

  1. 1.Department of Endocrinology, the Seventh People's Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200137, China; 2. Department of Hematology, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai 200080,China; 3. Department of Internal Medicine, Yueyang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200437,China

  • Online:2017-01-28 Published:2017-01-19

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摘要：

报道1例有甲状腺功能减退症病史16年的患者，因水肿1年就诊，完善检查发现患者存在肺动脉高压、多浆膜腔积液、脾脏肿大、高泌乳素血症。在常规抗心力衰竭治疗后患者水肿无好转，进一步完善免疫固定电泳及骨髓细胞学检查后明确诊断为POEMS综合征。

关键词: POEMS综合征, 甲状腺功能减退症, 肺动脉高压, 多浆膜腔积液

Abstract:

This paper reported 1 case of POEMS syndrome with 16-year hypothyroidism. The patient came to our hospital due to edema for 1 year. After perfect inspection, we found the patient had pulmonary hypertension, multiple serous cavity effusion, spleen enlargement and high serum prolactin. But after the conventional anti heart failure treatment, there was no improvement in the patient with edema. Finally after the electrophoresis and bone marrow cytology, the patient was diagnosed as POEMS syndrome.

Key words: POEMS syndrome, hypothyroidism, pulmonary hypertension, multiple serous cavity effusion