上海交通大学学报（医学版）

上海交通大学学报（医学版） ›› 2017, Vol. 37 ›› Issue (12): 1653-.doi: 10.3969/j.issn.1674-8115.2017.12.013

• 论著（临床研究） • 上一篇    下一篇

葡萄膜炎患者的荧光素眼底血管造影及光学相干断层扫描的特点分析

陈娜，闫焱，李祯，陆士恒   

  1. 上海交通大学  医学院附属仁济医院眼科，上海 200127
  • 出版日期:2017-12-28 发布日期:2018-01-10
  • 通讯作者: 李祯，电子信箱：lizhen1981_1@126.com
  • 作者简介:陈娜（1984—），女，满族，住院医师，博士；电子信箱： chenna9972@163.com
  • 基金资助:
    上海交通大学医学院科技基金（14XJ10059）

Characteristic analysis of fundus fluorescein angiography and optical coherence tomography findings in uveitis#br#

CHEN Na, YAN Yan, LI Zhen, LU Shi-heng   

  1. Department of Ophthalmology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200127, China
  • Online:2017-12-28 Published:2018-01-10
  • Supported by:
     Science and Technology Fund of Shanghai Jiao Tong University School of Medicine,14XJ10059

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摘要：  目的 · 分析葡萄膜炎患者的荧光素眼底血管造影（FFA）和光学相干断层扫描（OCT）的特点。方法 · 纳入上海交通大学 医学院附属仁济医院2015 年 4 月—2017 年 8 月收治的84 例（135 眼）葡萄膜炎患者，总结分析FFA 和 OCT 检查的图像特征。 结果 · 84 例葡萄膜炎患者，平均年龄（44±10）岁，男性多于女性。双眼同时或先后发病的有 51 例（102 眼），单眼发病的有 33 例 （33 眼）。 FFA 检查可见常见表现为视盘强荧光（73%）和血管壁染色（50%）； OCT 检查可见患者表现为黄斑囊样水肿（23%）和神 经上皮脱离（21%）。 OCT 检查所示的常见阳性表现的比例（10% ～ 40%）低于 FFA 检查所示的常见阳性表现的比例（23% ～ 100%） （χ2=33.8，P=0.000）。 结论 · 葡萄膜炎常见于中青年男性，FFA 检查发现常见的表现为视盘强荧光、血管壁染色，OCT 检查发现常见 的表现为黄斑囊样水肿、神经上皮脱离。

关键词: &ensp, 葡萄膜炎；荧光素眼底血管造影；光学相干断层扫描

Abstract:

Objective · To investigate the characteristics of fundus fluorescein angiography (FFA) and optical coherence tomography (OCT) findings of patients with uveitis.  Methods · The clinical data of 84 patients (135 eyes) diagnosed as uveitis in Renji Hospital, Shanghai Jiao Tong University School of Medicine from Apr 2015 to Aug 2017 were studied retrospectively. FFA and OCT examinations were performed.  Results · Of 84 patients, the average age was (44±10) years old. There were more males than females. Fifty-one patients (102 eyes) were affected bilaterally, and 33 patients (33 eyes) were affected unilaterally. Optic fluorescence leakage was found in 73% of patients, and retinal vascular wall staining was found in 50% of patients by FFA. Cystoid macular edema was found in 23% of patients, and neuroepithelial detachment was found in 21% of patients by OCT. The proportion of common positive manifestation by OCT (10%–40%) was lower than that by FFA (23%–100%) (χ2=33.8, P=0.000).  Conclusion · The uveitis usually occurs in young and middle-aged male patients. The most common features of the uveitis patients are optic fluorescence leakage and retinal vascular wall staining by FFA, and cystoid macular edema and neuroepithelial detachment by OCT.

Key words: uveitis, fundus fluorescein angiography, optical coherence tomography