上海交通大学学报（医学版）

上海交通大学学报（医学版）

• 论著（临床研究） • 上一篇    下一篇

CT能谱成像对垂体腺瘤质地判断的应用价值

侯国强1，谢宝树1，贾 锋1，王 宇1，殷玉华1，陈增爱2   

  1. 上海交通大学 医学院附属仁济医院 1.神经外科， 2.放射科， 上海 200127
  • 出版日期:2014-05-28 发布日期:2014-05-30
  • 通讯作者: 殷玉华, 电子信箱: yinyuhuacn@163.com; 陈增爱, 电子信箱: chenzengai@163.com。
  • 作者简介:侯国强（1987—）， 男， 硕士生; 电子信箱: houaima1987@163.com。

Application value of spectral computed tomography imaging for judgment of texture of pituitary adenoma

HOU Guo-qiang1, XIE Bao-shu1, JIA Feng1, WANG Yu1, YIN Yu-hua1, CHEN Zeng-ai2   

  1. 1.Department of Neurosurgery, 2.Department of Radiology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200127, China
  • Online:2014-05-28 Published:2014-05-30

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摘要：

目的 探讨CT能谱成像在垂体腺瘤质地判断方面的应用价值。方法 收集2011年12月—2013年11月收治的36例垂体腺瘤患者的临床资料，根据术中所见腺瘤质地分为质地软组、质地中等组和质地韧组；患者术前均行头颅磁共振成像（MRI）增强和计算机化断层显像（CT）能谱成像增强扫描检查，对腺瘤组织和额叶白质的能谱衰减曲线及其斜率进行分析和比较。结果 36例垂体腺瘤中，质地软组24例，质地中等组8例，质地韧组4例，腺瘤组织CT能谱衰减曲线斜率分别为0.669±0.066、0.333±0.024和0.145±0.049，腺瘤组织与额叶白质的能谱衰减曲线斜率的比值分别为1.355±0.279、0.674±0.057和0.318±0.005，组间比较差异均有统计学意义（P<0.001）。结论 术前CT能谱成像检查有助于对垂体腺瘤质地进行判断，衰减曲线腺瘤斜率及其与额叶白质斜率的比值与垂体腺瘤的质地有关。

关键词: CT能谱成像, 垂体腺瘤, 质地

Abstract:

Objective To explore the application value of spectral computed tomography (CT) imaging for the judgment of texture of pituitary adenoma. Methods Clinical data of 36 patients treated for pituitary adenoma between December, 2011 and November, 2013 were collected. Cases were divided into the soft group, medium group, and tough group according to textures of tumors found during operations. Patients were examined by MRI and spectral CT enhanced scan before operations. Spectral attenuation curves of tumor tissues and frontal white matter and their slopes were analyzed and compared. Results Among 36 cases of pituitary adenoma, 24 cases belonged to the soft group; 8 cases belonged to the medium group; and 4 cases belonged to the tough group. Their slopes of CT spectral attenuation curves of tumor tissues were 0.669±0.066, 0.333±0.024, and 0.145±0.049, respectively. The ratios of slopes of spectral attenuation curves of tumor tissues and frontal white matter were 1.355±0.279, 0.674±0.057, and 0.318±0.005. The differences among groups were statistically significant (P<0.001). Conclusion Preoperative spectral CT imaging examination is helpful for judging the texture of pituitary adenoma. The ratio of slopes of attenuation curves of the tumor tissue and frontal white matter is relevant to the texture of pituitary adenoma.

Key words: spectral computed tomography imaging, pituitary adenomas, texture