上海交通大学学报（医学版）

上海交通大学学报（医学版）

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精神外科：从毁损术到神经调控技术

许珮玮，江开达，徐一峰，刘登堂   

  1. 上海交通大学 医学院附属精神卫生中心精神病性障碍科，上海 200030
  • 出版日期:2017-02-28 发布日期:2017-02-28
  • 通讯作者: 刘登堂，电子信箱：erliu110@126.com。
  • 作者简介:许珮玮（1993—），女，硕士生；电子信箱：xupeiwei93@outlook.com。
  • 基金资助:

    国家自然科学基金（81371479）；上海市科学技术委员会引导类项目(15411964400)；上海市卫生和计划生育委员会项目（2014ZYJB0002，20134006)；上海市市级医院适宜技术项目(SHDC12014214)；上海市精神疾病临床医学中心项目（2014）；上海市精神卫生中心早期精神病性障碍科项目（2013-YJTSZK-05）

Psychosurgery: from ablation to neuromodulation

XU Pei-wei, JIANG Kai-da, XU Yi-feng, LIU Deng-tang   

  1. Division of Psychotic Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai 200030, China
  • Online:2017-02-28 Published:2017-02-28
  • Supported by:

    National Natural Science Foundation of China, 81371479; Foundation of Science and Technology Commission of Shanghai Municipality, 15411964400; Foundation of Shanghai Municipal Health and Family Planning Commission, 2014ZYJB0002, 20134006, 20144Y0054; Shanghai Municipal Hospital Appropriate Technology Programme, SHDC12014214; Project of Shanghai Clinical Center for Mental Disorders, 2014; Early Psychosis Program of Shanghai Mental Health Center, 2013-YJTSZK-05

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摘要：

精神外科是指精神疾病的神经外科治疗，有着漫长而富有争议的历史。该文系统综述了精神外科的诞生，额叶白质切断术的繁荣与其后的没落，立体定向技术的发展及常用术式，以及现代神经调控技术（包括经颅磁刺激，迷走神经刺激及深部脑刺激等）的新发展，最后讨论了国内精神外科发展现状，并提出对未来的展望。

关键词: 精神外科, 额叶白质切断术, 立体定向技术, 神经调控技术

Abstract:

Psychosurgery, the neurosurgical treatment for psychiatric disorders, has a long and controversial history. The review introduces the birth of psychosurgery, the rise and fall of the frontal lobotomy and the transition to the modern era of psychosurgery, due to the development of the stereotactic instruments, and the different psychosurgical procedures. Today, recent advances in neuromodulation may provide an opportunity for psychosurgery to become a more attractive option for the treatment of psychiatric diseases. Current states in China and prospects of psychosurgery are also discussed.

Key words: psychosurgery, frontal leucotomy, stereotactic techniques, neuromodulation