上海交通大学学报（医学版）

›› 2013, Vol. 33 ›› Issue (4): 523-.doi: 10.3969/j.issn.1674-8115.2013.04.031

• 短篇论著 • 上一篇    下一篇

经颅超声多普勒技术联合血浆肾上腺髓质素检测对椎基底动脉供血不足的临床评估

朱秀丽, 朱昱思, 舒晓丹   

  1. 武警上海市总队医院特检科, 上海 201103
  • 出版日期:2013-04-28 发布日期:2013-05-03
  • 作者简介:朱秀丽（1972—）, 女, 副主任技师, 学士； 电子信箱: hifen2006go@hotmail.com。

Clinical evaluation of vertebrobasilar ischemia by transcranial doppler ultrasonography and plasma adrenomedullin

ZHU Xiu-li, ZHU Yu-si, SHU Xiao-dan   

  1. Department of Special Examination, Shanghai Municipal Crops Hospital of Armed Police Force, Shanghai 201103, China
  • Online:2013-04-28 Published:2013-05-03

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摘要：

目的 探讨经颅超声多普勒（TCD）技术联合血浆肾上腺髓质素（ADM）检测对椎基底动脉供血不足（VBI）的临床评估作用。方法 分析50例临床诊断为VBI患者（VBI组）的TCD资料，记录椎动脉(VA)和基底动脉(BA)的血管峰值收缩期流速(Vs)、舒张末期流速(Vd)、平均血流速度(Vm)、搏动指数(PI)以及血浆ADM值等，并与同期50名正常人群（对照组）进行比较。结果 VBI组VA和BA的Vm、Vs以及Vd明显低于对照组；PI高于对照组，两组比较差异有统计学意义(P<0.05)；VBI组血浆ADM值明显高于对照组，差异有统计学意义（P<0.05）。结论 TCD联合血浆ADM检测可为VBI患者病情及治疗评估提供依据。

关键词: 经颅超声多普勒, 椎基底动脉供血不足, 血浆肾上腺髓质素

Abstract:

Objective To investigate the role of transcranial doppler ultrasonography (TCD) and plasma adrenomedullin (ADM) in evaluation of vertebrobasilar ischemia (VBI). Methods The data of TCD of 50 patients with VBI (VBI group) were analysed. The systolic velocity (Vs), diastolic velocity (Vd), mean velocity (Vm), pulsatility index (PI) and plasma ADM of vertebral artery (VA) and basilar artery (BA) of VBI group were recorded, and were compared with those of 50 healthy normal people (control group). Results The parameters of Vm, Vs and Vd of VA and BA in VBI group were significantly lower than those in control group (P<0.05), and PI in VBI group was significantly higher than that in control group (P<0.05). The plasma ADM in VBI group was significantly higher than that in control group (P<0.05). Conclusion TCD combined with plasma ADM can serve in the evaluation of disease condition and treatment in patients with VBI.

Key words: transcranial doppler ultrosonography, vertebrobasilar ischemia, plasma adrenomedullin