网络出版日期: 2016-01-13
基金资助
国家自然科学基金(81101073,81471708);上海交通大学医工(理)交叉研究基金(YG2012MS13)
Advances of radionuclide imaging for cell apoptosis
Online published: 2016-01-13
Supported by
National Natural Science Foundation of China, 81101073, 81471708; Biomedical Engineering Cross Research Foundation of Shanghai Jiao Tong University, YG2012MS13
刘秋芳 , 宋少莉 . 核素细胞凋亡显像剂的研究进展[J]. 上海交通大学学报(医学版), 2015 , 35(11) : 1743 . DOI: 10.3969/j.issn.1674-8115.2015.11.029
Radionuclide imaging for the cell apoptosis is a direct, noninvasive, and real-time imaging technique. It is a hopeful method for observing brain and myocardial ischemic reperfusion injury, detecting allograft rejection, and evaluating the effects of tumor chemotherapy and radiotherapy. This paper introduces the design, mechanisms, and applications of radionuclide agents based on preclinical studies.
Key words: apoptosis; radionuclide agent; phosphatidylserine; Annexin; synaptotagmin Ⅰ; caspase
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