法尼醇 X受体（farnesol X receptor，FXR），又称为胆汁酸核受体，是配体依赖性的核转录因子，可分布于体内肝脏、肠道等多个组织器官；胆汁酸是其内源性天然配体。近年有研究表明，肠道 FXR对于糖脂代谢调节具有不可或缺的作用，肠道特异性 FXR激动剂或抑制剂均可参与体内糖脂代谢调节。该文对近年来报道的肠道 FXR在糖脂代谢中的作用进行系统的综述。

Farnesol X receptor (FXR), also known as bile acid nuclear receptor, is a ligand-dependent nuclear transcription factor distributed in multiple tissues and organs such as liver and intestinal tract. And bile acid is its endogenous natural ligand. Recent studies have shown that intestinal FXR plays an indispensable role in glycolipid metabolism regulation, and intestinal specific FXR agonists or antagonists can participate in glucose and lipid metabolism regulation in vivo. In this paper, the role of intestinal FXR in glycolipid metabolism reported in recent years is systematically reviewed.