冠状动脉粥样硬化性心脏病（冠心病）是临床常见疾病，其发病率与死亡率居高不下。近年来，随着人们生活水平的提高以及生活方式的改变,冠心病的发病年龄趋于年轻化。该文根据国内外研究现状，探讨了与早发冠心病相关的遗传因素、临床危险因素、炎症指标及新型炎症标志物，分析了女性早发冠心病的特殊性，并指出早发冠心病以遗传因素为主，心理因素等多种危险因素共同参与，与炎性指标密切相关。新型炎症标志物的出现对早发冠心病的预测、诊断和治疗具有一定的价值。

Coronary artery heart disease (CHD) is a common clinical disease with high morbidity and mortality. In recent years, with the improvement of people's living standards and the changes of lifestyle, the age of CHD tends to be younger. Based on the present research situation at home and abroad, this paper explores the hereditary factors, clinical risk factors, inflammatory indexes and new inflammatory markers related to the diagnosis and treatment of premature CHD (PCHD). And the particularity of PCHD in women is analyzed. It is pointed out that PHD is dominated by hereditary factors, with multiple risk factors participating together including psychological factors, and closely related to inflammatory indicators. The emergence of new inflammatory markers provides certain value for the prediction, diagnosis and treatment of PCHD.