上海交通大学学报（医学版）

上海交通大学学报（医学版） >

2022 , Vol. 42 >Issue 1: 77 - 81

DOI: https://doi.org/10.3969/j.issn.1674-8115.2022.01.011

论著 · 临床研究

精神运动康复对稳定期精神分裂症患者阴性症状及认知功能的影响

  • 陆如平 ,
  • 高慧 ,
  • 蒋琳娜 ,
  • 陈晓亚 ,
  • 彭红 ,
  • 沈辉 ,
  • 范青
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  • 1.上海市民政第一精神卫生中心精神科，上海 201105
    2.上海交通大学医学院附属精神卫生中心康复科，上海 200030
陆如平（1974—），男，副主任医师，学士；电子信箱：LRP2001@163.com。
范青，电子信箱：fanqing@smhc.org.com。

收稿日期: 2021-04-21

  网络出版日期: 2022-01-28

基金资助

上海市“科技创新行动计划”临床医学领域项目(19411950800);上海市2020年度“科技创新行动计划”科普专项(20DZ2311500)

收起

Effect of psychomotor therapy on negative symptoms and cognitive function of patients with stable schizophrenia

  • Ruping LU ,
  • Hui GAO ,
  • Linna JIANG ,
  • Xiaoya CHEN ,
  • Hong PENG ,
  • Hui SHEN ,
  • Qing FAN
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  • 1.Department of Psychiatry, Shanghai No. 1 Civil Mental Health Center, Shanghai 201105, China
    2.Department of Rehabilitation, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai 200030, China
FAN Qing, E-mail: fanqing@smhc.org.com.

Received date: 2021-04-21

  Online published: 2022-01-28

Supported by

Shanghai “Science and Technology Innovation Action Plan” Clinical Medicine Project(19411950800);Science Popularization Project of Shanghai′s 2020 “Science and Technology Innovation Action Plan”(20DZ2311500)

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摘要

目的·探究精神运动康复对稳定期精神分裂症患者的阴性症状和认知功能的改善作用。方法·采用随机数字表将上海市民政第一精神卫生中心的64例稳定期精神分裂症患者分为研究组及对照组；2组对象均给予常规的治疗、护理及日常康复，研究组在此基础上予以精神运动康复干预，干预周期为10周；分别于入组前后对2组患者进行阳性和阴性症状量表（Positive and Negative Symptom Scale，PANSS）、简易智力状态检查（Mini Mental State Examination，MMSE）、重复性成套神经心理状态测验（Repeatable Battery for the Assessment of Neuropsychological Status，RBANS）评估。结果·研究组及对照组分别有30例患者完成观察。重复测量方差分析结果显示，干预10周后，研究组PANSS的阴性症状分量表得分、PANSS总分低于对照组（均P=0.000），而MMSE、RBANS得分高于对照组（P=0.008，P=0.000）；10周后研究组PANSS的阴性症状分量表得分、PANSS总分低于研究前（均P=0.000），而MMSE、RBANS得分高于研究前（均P=0.000）。结论·精神运动康复可以改善稳定期精神分裂症患者的阴性症状，提高其认知功能水平。

关键词： 精神运动康复; 精神分裂症; 阴性症状; 认知功能

本文引用格式

陆如平 , 高慧 , 蒋琳娜 , 陈晓亚 , 彭红 , 沈辉 , 范青 . 精神运动康复对稳定期精神分裂症患者阴性症状及认知功能的影响[J]. 上海交通大学学报（医学版）, 2022 , 42(1) : 77 -81 . DOI: 10.3969/j.issn.1674-8115.2022.01.011

Abstract

Objective

·To explore the effect of psychomotor therapy on negative symptoms and cognitive function of patients with stable schizophrenia.

Methods

·A random number table was used to divide 64 stable schizophrenia patients from Shanghai No.1 Civil Mental Health Center into a study group and a control group. The control group was given routine treatment, nursing and daily rehabilitation, and the study group increased psychomotor therapy on this basis. Both groups were intervened for 10 weeks, and the patients in the two groups were evaluated by the Positive and Negative Symptom Scale (PANSS), Mini Mental State Examination (MMSE), and the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) before and after the intervention.

Results

·Thirty patients in the study group and the control group completed the observation. The repeated-measures analysis of variance (ANOVA) showed that after 10 weeks of intervention, the score of PANSS negative symptom subscale and PANSS total score were lower than those of the control group (all P=0.000), while the scores of MMSE and RBANS were higher than those of the control group (P=0.008, P=0.000). After 10 weeks, the negative symptom subscale score and PANSS total score of the study group were lower than those before the study (all P=0.000), while the MMSE and RBANS scores were higher than those before the study (all P=0.000).

Conclusion

·Psychomotor therapy can improve the negative symptoms and cognitive function of patients with stable schizophrenia.

Key words： psychomotor therapy; schizophrenia; negative symptom; cognitive function

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