收稿日期: 2024-11-20
录用日期: 2025-01-07
网络出版日期: 2025-04-21
Brugada phenocopy induced by heatstroke: a case report
Received date: 2024-11-20
Accepted date: 2025-01-07
Online published: 2025-04-21
患者男性，56岁，因“被发现神志不清伴体温升高1 d”于急诊就诊。同时有凝血功能障碍、呼吸衰竭、肝肾功能异常、胃肠功能紊乱等多器官功能障碍的临床表现，排除其他疾病后诊断为热射病；并且该患者有相对突出的心肌损伤表现，心电图显示ST段抬高、Brugada波，考虑热射病相关心肌损伤并且致Brugada拟表型。这种表现可能与心肌热损伤、热应激后的全身炎症反应、温度敏感的离子通道功能异常等多种机制有关。临床需加强对热射病相关心肌损伤和Brugada拟表型的认识，以改善热射病的治疗与预后。
关键词： 热射病; 心肌损伤; ST段抬高; Brugada拟表型
李遥敏 , 徐建国 , 于霞 . 热射病致Brugada拟表型1例[J]. 上海交通大学学报（医学版）, 2025 , 45(4) : 523 -528 . DOI: 10.3969/j.issn.1674-8115.2025.04.016
The patient, a 56-year-old male, was admitted to the emergency department due to confusion and elevated body temperature persisting for 1 d. He presented with multiple organ dysfunction, including coagulation dysfunction, respiratory failure, abnormal liver and kidney function, and gastrointestinal disorders. After excluding other potential causes, a diagnosis of heatstroke was made. Additionally, the patient exhibited myocardial injury and Brugada phenocopy, as evidenced by ST-segment elevation and Brugada wave on electrocardiogram. These findings may be related to several mechanisms such as myocardial thermal injury, systemic inflammatory response after heat stress, and abnormal function of temperator-sensitive ion channels. It is necessary to strengthen the understanding of heatstroke-related myocardial injury and Brugada phenotypy to help improve the treatment and prognosis of heatstroke.
Key words： heatstroke; myocardial injury; ST-segment elevation; Brugada phenocopy
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