论著 · 基础研究

基于数字光处理技术的牙科冠桥树脂制备及其打印参数优化研究

  • 刘俊龙 ,
  • 马佳音 ,
  • 赵喆 ,
  • 熊耀阳 ,
  • 郑元俐
展开
  • 1.上海交通大学医学院附属第九人民医院第一口腔门诊,上海交通大学口腔医学院,国家口腔医学中心,国家口腔疾病临床医学研究中心,上海市口腔医学重点实验室,上海市口腔医学研究所,上海 200011
    2.上海交通大学医学院附属第九人民医院口腔修复科,上海交通大学口腔医学院,国家口腔医学中心,国家口腔疾病临床医学研究中心,上海市口腔医学重点实验室,上海市口腔医学研究所,上海 200011
    3.上海应用技术学院材料科学与工程学院,上海 201418
第一联系人:刘俊龙、 马佳音为共同第一作者(co-first authors)。
郑元俐,教授,博士;电子信箱:zhengyuanli2017@163.com
熊耀阳,副主任医师,博士;电子信箱:yaoyang_x@163.com
赵 喆,教授,博士;电子信箱:zhezhao@sit.edu.cn

收稿日期: 2024-11-26

  录用日期: 2025-03-05

  网络出版日期: 2025-07-28

基金资助

上海市卫生健康委员会卫生行业临床研究专项(202440008);上海市自然科学基金(23ZR1453600)

Optimization of optimal printing parameters and composition ratio of dental crown and bridge resin based on digital light processing technology

  • LIU Junlong ,
  • MA Jiayin ,
  • ZHAO Zhe ,
  • XIONG Yaoyang ,
  • ZHENG Yuanli
Expand
  • 1.Department of First Dental Clinic, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine; College of Stomatology, Shanghai Jiao Tong University; National Center for Stomatology; National Clinical Research Center for Oral Diseases; Shanghai Key Laboratory of Stomatology; Shanghai Research Institute of Stomatology, Shanghai 200011, China
    2.Department of Prosthodontics, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine; College of Stomatology, Shanghai Jiao Tong University; National Center for Stomatology; National Clinical Research Center for Oral Diseases; Shanghai Key Laboratory of Stomatology; Shanghai Research Institute of Stomatology, Shanghai 200011, China
    3.School of Material Science and Engineering, Shanghai Institute of Technology, Shanghai 201418, China
ZHENG Yuanli, E-mail: zhengyuanli2017@163.com.
XIONG Yaoyang, E-mail: yaoyang_x@163.com.
ZHAO Zhe, E-mail: zhezhao@sit.edu.cn.

Received date: 2024-11-26

  Accepted date: 2025-03-05

  Online published: 2025-07-28

Supported by

Health Industry Clinical Research Special Project of Shanghai Health Commission(202440008);Natural Science Foundation of Shanghai(23ZR1453600)

摘要

目的·构建基于数字光处理(digital light processing,DLP)技术成形的3D打印牙科冠桥树脂浆料,研究不同打印参数对其机械性能的影响,确定最佳打印参数,优化DLP打印冠桥树脂的成分比例。方法·基于混合物黏度特性,探究二甲基丙烯酸氨基甲酸酯(urethane dimethacrylate,UDMA)与聚乙二醇甲基丙烯酸二酯[poly (propylene glycol) dimethacrylate,PPGDMA]的最佳配比;对纳米二氧化硅(silicon dioxide,SiO2)进行硅烷化处理后,与UDMA、PPGDMA以及2,4,6-三甲基苯甲酰基二甲苯基氧化膦[2,4,6-trimethylbenzoyl bis (p-tolyl) phosphine oxide,TMO]混合,制备不同固含量的DLP打印冠桥树脂浆料,测试其流变性能;利用Beer-Lambert方程计算打印浆料的光穿透深度(Dp)及临界曝光能量(Ec);基于浆料的光穿透深度和临界曝光能量,分别设置不同曝光强度、曝光时间、后固化时间和层厚,开展一系列打印实验。通过对比分析不同打印参数下成品的抗弯强度,筛选出最优打印参数组合。结果·通过测试UDMA和PPGDMA不同比例的黏度值,确定UDMA与PPGDMA的最佳配比为6∶4;对不同固含量的打印浆料进行流变行为测试,结果显示,固含量为22%的DLP打印冠桥树脂展现出最佳打印性能;经Beer-Lambert方程拟合分析,计算出打印浆料的Dp=119.79 μm,Ec=25.54 mJ/cm2。测试不同曝光强度下的抗弯性能,发现当曝光强度为20 mW/cm2时,弯曲强度值达到最大值(132.39±8.92)MPa,且差异具有统计学意义(P<0.05);不同曝光时间的抗弯结果显示,单层曝光时间3.0 s时弯曲强度即可达到(131.73±9.43)MPa,继续增加曝光时间,无显著差异;不同后固化时间的抗弯结果显示,当后固化时间达到30 min后,随着后固化时间增加,弯曲强度值无显著变化;关于不同层厚对抗弯性能的影响,测试结果显示,当层厚为50 μm时,结果表现最优,且差异具有统计学意义(P<0.001)。结论·经过黏度和流变性能测试,成功制备出适用于DLP打印的冠桥树脂浆料。通过对不同打印参数下抗弯强度的统计学分析,最终确定最佳打印参数组合:曝光强度为20 mW/cm2,曝光时间为3.0 s,后固化时间为30 min,层厚设定为50 μm。

本文引用格式

刘俊龙 , 马佳音 , 赵喆 , 熊耀阳 , 郑元俐 . 基于数字光处理技术的牙科冠桥树脂制备及其打印参数优化研究[J]. 上海交通大学学报(医学版), 2025 , 45(7) : 858 -865 . DOI: 10.3969/j.issn.1674-8115.2025.07.007

Abstract

Objective ·To fabricate a 3D-printed dental crown and bridge resin slurry using digital light processing (DLP) technology, investigate the influence of different printing parameters on its mechanical properties, determine the optimal printing parameters, and optimize the composition ratio of DLP-printed crown and bridge resin. Methods ·Based on the viscosity characteristics of the mixture, the optimal ratio of urethane dimethacrylate (UDMA) to poly (propylene glycol) dimethacrylate (PPGDMA) was explored. After silanizing silicon dioxide (SiO2), it was mixed with UDMA, PPGDMA, and 2,4,6-trimethylbenzoyl bis (p-tolyl) phosphine oxide (TMO) to prepare DLP-printed dental crown and bridge resin slurries with different solid contents, and their rheological properties were tested. The Beer-Lambert equation was used to calculate the light penetration depth and critical exposure energy of the printing slurry. Based on these values, different exposure intensities, exposure times, post-curing times, and layer thicknesses were set respectively to carry out a series of printing experiments. By comparing and analyzing the flexural strength of the products under different printing parameters, the optimal printing parameter combination was screened out. Results ·Viscosity tests showed that the optimal UDMA-to-PPGDMA ratio was 6∶4. The rheological behavior of printing slurries with different solid contents was tested, and the results showed that the DLP-printed dental crown and bridge resin with a solid content of 22% exhibited the best printing performance. According to the Beer-Lambert analysis, the light penetration depth Dp of the printing slurry was 119.79 μm, and the critical exposure energy Ec was 25.54 mJ/cm2. When the exposure intensity was 20 mW/cm², the flexural strength reached a maximum of (132.39±8.92) MPa, and the difference was statistically significant (P<0.05). The flexural results of different exposure times showed that the flexural strength could reach (131.73±9.43) MPa when the single-layer exposure time was 3.0 s, and there was no significant difference when the exposure time was further increased. The flexural results of different post-curing times showed that when the post-curing time reached 30 min, there was no significant relationship between the flexural strength value and the increase in post-curing time. Regarding the influence of different layer thicknesses on the flexural performance, the test results showed that when the layer thickness was 50 μm, the result was the best, and the difference was statistically significant (P<0.001). Conclusion ·Based on viscosity and rheological tests, a DLP-printable crown and bridge resin slurry was successfully developed. The optimal printing parameters were determined through statistical analysis of flexural strength: exposure intensity of 20 mW/cm², exposure time of 3.0 s, post-curing time of 30 min, and a layer thickness of 50 μm.

参考文献

[1] STANSBURY J W, IDACAVAGE M J. 3D printing with polymers: challenges among expanding options and opportunities[J]. Dent Mater, 2016, 32(1): 54-64.
[2] REVILLA-LEóN M, MEYERS M J, ZANDINEJAD A, et al. A review on chemical composition, mechanical properties, and manufacturing work flow of additively manufactured current polymers for interim dental restorations[J]. J Esthet Restor Dent, 2019, 31(1): 51-57.
[3] ALHARBI N, OSMAN R, WISMEIJER D. Effects of build direction on the mechanical properties of 3D-printed complete coverage interim dental restorations[J]. J Prosthet Dent, 2016, 115(6): 760-767.
[4] LING L, TAREMI N, MALYALA R. A novel low-shrinkage resin for 3D printing[J]. J Dent, 2022, 118: 103957.
[5] EMAMI N, SJ?DAHL M, S?DERHOLM K M. How filler properties, filler fraction, sample thickness and light source affect light attenuation in particulate filled resin composites[J]. Dent Mater, 2005, 21(8): 721-730.
[6] CRAIG R G, PEYTON F A. Elastic and mechanical properties of human dentin[J]. J Dent Res, 1958, 37(4): 710-718.
[7] LI Z H, WANG J J, CHEN H Y, et al. Synthesis of ZnO nanorod-decorated graphene oxide for application in dental resin composites[J]. ACS Biomater Sci Eng, 2023, 9(5): 2706-2715.
[8] WALTERS N J, XIA W, SALIH V, et al. Poly(propylene glycol) and urethane dimethacrylates improve conversion of dental composites and reveal complexity of cytocompatibility testing[J]. Dent Mater, 2016, 32(2): 264-277.
[9] PROTOPAPA P, KONTONASAKI E, BIKIARIS D, et al. Reinforcement of a PMMA resin for fixed interim prostheses with nanodiamonds[J]. Dent Mater J, 2011, 30(2): 222-231.
[10] AI M, DU Z Y, ZHU S Q, et al. Composite resin reinforced with silver nanoparticles-laden hydroxyapatite nanowires for dental application[J]. Dent Mater, 2017, 33(1): 12-22.
[11] PERSSON C, UNOSSON E, AJAXON I, et al. Nano grain sized zirconia-silica glass ceramics for dental applications[J]. J Eur Ceram Soc, 2012, 32(16): 4105-4110.
[12] KUMAR P, KUMAR V, KUMAR R, et al. Fabrication and characterization of ZrO2 incorporated SiO2-CaO-P2O5 bioactive glass scaffolds[J]. J Mech Behav Biomed Mater, 2020, 109: 103854.
[13] DELLA BONA A, CANTELLI V, BRITTO V T, et al. 3D printing restorative materials using a stereolithographic technique: a systematic review[J]. Dent Mater, 2021, 37(2): 336-350.
[14] OSMAN R B, ALHARBI N, WISMEIJER D. Build angle: does it influence the accuracy of 3D-printed dental restorations using digital light-processing technology?[J]. Int J Prosthodont, 2017, 30(2): 182-188.
[15] CHAIJAREENONT P, TAKAHASHI H, NISHIYAMA N, et al. Effect of different amounts of 3-methacryloxypropyltrimethoxysilane on the flexural properties and wear resistance of alumina reinforced PMMA[J]. Dent Mater J, 2012, 31(4): 623-628.
[16] LEE T, KIM J H, NG C S, et al. Prediction of curing depth dependence on CNT nanofiller dispersion for vat photopolymerization 3D printing[J]. Chem Eng J, 2024, 482: 149110.
[17] VAN N R. The future of dental devices is digital[J]. Dent Mater, 2012, 28(1): 3-12.
[18] BRAIAN M, JIMBO R, WENNERBERG A. Production tolerance of additive manufactured polymeric objects for clinical applications[J]. Dent Mater, 2016, 32(7): 853-861.
[19] PAR M, MOHN D, ATTIN T,et al. Polymerization shrinkage behaviour of resin composites functionalized with unsilanized bioactive glass fillers[J]. Sci Rep, 2020, 10(1): 15237.
[20] MOSZNER N, SALZ U. New developments of polymeric dental composites[J]. Prog Polym Sci, 2001, 26(4): 535-576.
[21] YAO Y X, CUI H B, WANG W Q, et al. High performance dental zirconia ceramics fabricated by vat photopolymerization based on aqueous suspension[J]. J Eur Ceram Soc, 2024, 44(16): 116795.
[22] GAD M M, FOUDA S M, ABUALSAUD R, et al. Strength and surface properties of a 3D-printed denture base polymer[J]. J Prosthodont, 2022, 31(5): 412-418.
[23] KHAN S B, LI N, LIANG J H, et al. Influence of exposure period and angle alteration on the flexural resilience and mechanical attributes of photosensitive resin[J]. Nanomaterials (Basel), 2022, 12(15): 2566.
[24] GU Y, DUAN W Y, WANG T C, et al. Additive manufacturing of Al2O3 ceramic core with applicable microstructure and mechanical properties via digital light processing of high solid loading slurry[J]. Ceram Int, 2023, 49(15): 25216-25224.
文章导航

/