网络出版日期: 2010-11-29
基金资助
国家自然科学基金(30973382)
Research progress of role of matrix metalloproteinase 7 in tumors
Online published: 2010-11-29
Supported by
National Natural Science Foundation of China, 30973382
黄 勇, 郑 树 . 基质金属蛋白酶7在肿瘤中的作用研究进展[J]. 上海交通大学学报(医学版), 2010 , 30(11) : 1428 . DOI: 10.3969/j.issn.1674-8115.2010.11.027
Matrix metalloproteinase 7 (MMP7) plays an important role in tumorigenesis, tumor development and resistance to some anti-tumor medicine by degrading proteins of extracellular matrix and blocking fas/fasl apoptosis signal pathway. This paper discusses the mechanisms by which MMP7 contribute to carcinogenesis, and the research progress of MMP7 in tumor treatment.
Key words: matrix metalloproteinase 7; fas/fasl; apoptosis; neoplasm
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