子癎前期-子癎并发症发生机制的研究
Pathogenesis of complications of pre-eclampsia and eclampsia
Online published: 2011-05-27
乐怡平, 林建华 . 子癎前期-子癎并发症发生机制的研究[J]. 上海交通大学学报(医学版), 2011 , 31(5) : 676 . DOI: 10.3969/j.issn.1674-8115.2011.05.032
Pre-eclampsia is a disorder that is unique to pregnancy, with gestational hypertension and proteinuria as main clinical manifestations. Without proper management, pre-eclampsia may develop to eclampsia and cause a series of complications involving cardiovascular, renal, neurologic, hematologic and gastrointestinal systems, which may threaten lives of mothers and infants. The pathogenesis of pre-eclampsia is still unclear, and reduced placental perfusion is considered to be the pathological mechanism, which may result in endothelial cell injury and further aggravate dysfunction of maternal systems. This paper reviews the pathogenesis, incidence and research progress of complications of pre-eclampsia and eclampsia.
Key words: pre-eclampsia; eclampsia; complication
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